Results 31 to 40 of about 262,483 (141)

GSK3 maintains NSP12 stability to promote bat-origin swine acute diarrhea syndrome coronavirus infection [PDF]

Journal of Virology
Bat-origin swine acute diarrhea syndrome coronavirus (SADS-CoV) causes diarrhea and death in piglets and also poses a cross-species transmission risk due to its broad host cell tropism.
Maowen Sun, Cong Yuan, Yueyue Duan, Lei Shi, Yu Zhang, Luyao Li, Wenquan Mao, Haixue Zheng, Qi Wang   +8 more
doaj   +2 more sources

Molecular characterization of swine acute diarrhea syndrome coronavirus detected in Vietnamese pigs

Veterinary Research
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a novel porcine coronavirus that was recently identified in southern China in 2017. At present, there is a lack of nationwide epidemiological investigations of the newly emerged SADS-CoV.
Nam Phuong Le, Bac Tran Le, Van Phan Le, Jung-Eun Park   +3 more
doaj   +2 more sources

Swine acute diarrhea syndrome coronavirus nsp5 induces apoptosis by targeting GATA zinc finger domain-containing protein 2A (GATAD2A/p66α) [PDF]

mBio
Swine acute diarrhea syndrome coronavirus (SADS-CoV) causes severe enteric disease in neonatal piglets, resulting in substantial economic losses worldwide.
Haixin Huang, Xin Wang, Yan Qin, Yuying Li, Jiahan Gang, Xinyu Zhang, Lulu Xie, Yimin Zhou, Qiaoqiong Wang, Wei Chen, Yuanze Sun, Zaijuan Zhang, Xianfu Ke, Tian Lan, Wenchao Sun   +14 more
doaj   +2 more sources

Retraction: Epitopes screening and vaccine molecular design of SADS-CoV based on immunoinformatics. [PDF]

Front Vet Sci, 2023
Frontiers Editorial Office.
europepmc   +3 more sources

Re-emergence of Severe Acute Diarrhea Syndrome Coronavirus (SADS-CoV) in Guangxi, China, 2021 [PDF]

J Infect, 2022
Abstract Severe acute diarrhea syndrome coronavirus (SADS-CoV) has had a major impact on the swine industry in China, but has not been detected since 2019. Using real-time qPCR and metagenomic surveillance we identified SADS-CoV in a pig farm experiencing diarrheal disease.
Sun Y, Xing J, Xu Z, Gao H, Xu S, Liu J, Zhu D, Guo Y, Yang B, Chen X, Zheng Z, Wang H, Gong L, Holmes EC, Zhang G.   +14 more
europepmc   +4 more sources

SADS-CoV nucleocapsid protein antagonizes DAD1-mediated STING activation to prevent cytosolic DNA sensing

Cell Reports
Summary: The STING pathway is pivotal in defense against RNA viruses; however, its involvement in swine acute diarrhea syndrome coronavirus (SADS-CoV) infection remains unclear.
Yuying Li, Xinyu Zhang, Wei Chen, Yimin Zhou, Yanqing Hu, Yuanze Sun, Tian Lan, Lulu Xie, Yan Qin, Cancan Si, HuiJun Lu, Jiyong Zhou, Wenchao Sun   +12 more
doaj   +3 more sources

A Comparative Analysis of Coronavirus Nucleocapsid (N) Proteins Reveals the SADS-CoV N Protein Antagonizes IFN-β Production by Inducing Ubiquitination of RIG-I [PDF]

Frontiers in Immunology, 2021
Yao-Wei Huang, Yong-Le Yang, Qi-Zhang Liang   +2 more
exaly   +2 more sources

Broad Cell Tropism of SADS-CoV In Vitro Implies Its Potential Cross-Species Infection Risk. [PDF]

Virol Sin, 2021
Luo Y, Chen Y, Geng R, Li B, Chen J, Zhao K, Zheng XS, Zhang W, Zhou P, Yang XL, Shi ZL.   +10 more
europepmc   +4 more sources

Establishment of a recombinase polymerase amplification (RPA) fluorescence assay for the detection of swine acute diarrhea syndrome coronavirus (SADS-CoV). [PDF]

BMC Vet Res, 2022
Abstract Background Swine acute diarrhea syndrome coronavirus (SADS-CoV) causes acute vomiting and diarrhea in piglets, leading to significant financial losses for the pig industry. Recombinase polymerase amplification (RPA) is a rapid nucleic acid amplification technology used under constant temperature conditions.
Cong X, Zhu Y, Liu X, Lian Y, Huang B, Luo Y, Gu Y, Wu M, Shi Y.   +8 more
europepmc   +5 more sources

SADS-CoV-induced complete autophagy.

, 2023
(A and C) Vero E6 and ST cells are mock-infected or infected with SADS-CoV at the indicated time points (24 and 48 hpi), the cellular lysates are subjected to a western blotting analysis with anti-viral N and anti-p62 antibodies.
Jianfei Chen (3186999), Zhaoyang Jing (9110860), Haojie He (14761730), Hongyan Shi (1988656), Dakai Liu (10474934), Da Shi (1455439), Jingyun Ma (1885213), Tingshuai Feng (14761721), Li Feng (77923), Ling Zhou (51948), Jiyu Zhang (725001), Xin Zhang (35492), Mei Xue (163742), Jianbo Liu (315277), Jialin Zhang (320005), Zhaoyang Ji (14761727), Longjun Guo (315268), Liaoyuan Zhang (12157704), Miaomiao Zeng (14761724), Yang Wu (66682)   +19 more
core   +2 more sources