Results 71 to 80 of about 10,375,512 (398)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

September 2019-Printed Issue

open access: yesPatient Safety, 2019
Welcome to the first issue of Patient Safety! Brought to you by the Patient Safety Authority, an independent agency of the Commonwealth of Pennsylvania, this brand-new journal is unlike any other you’ve seen. Since patients are at the heart of everything
Patient Safety Authority
doaj   +1 more source

Reasoned opinion on the modification of the existing MRLs for fosetyl in potato, kiwi and certain spices [PDF]

open access: yesEFSA Journal, 2012
In accordance with Article 6 of Regulation (EC) No 396/2005, France, hereafter referred to as the evaluating Member State France (EMS France), received an application from Bayer CropScience to modify the existing MRL for fosetyl-Al in kiwi.
European Food Safety Authority
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Why cultural safety rather than cultural competency is required to achieve health equity: a literature review and recommended definition

open access: yesInternational Journal for Equity in Health, 2019
BackgroundEliminating indigenous and ethnic health inequities requires addressing the determinants of health inequities which includes institutionalised racism, and ensuring a health care system that delivers appropriate and equitable care.
E. Curtis   +6 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Food Safety

open access: yesAnalytical Sciences, 2019
Food Safety is a key component of global challenges to both health and resources and is becoming increasingly complex given the global dimensions of food supply, the need to reduce food waste, and the growing importance of the efficient use of natural ...
H. Shiigi
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

March 2020-Printed Issue

open access: yesPatient Safety, 2020
The spring 2020 issue of _Patient Safety_ is available to read online and download at no charge. Each issue of Patient Safety brings you the latest evidence-based research and data analytics, interviews with healthcare experts and advocates, thought ...
Patient Safety Authority
doaj   +1 more source

Design for safety: theoretical framework of the safety aspect of BIM system to determine the safety index [PDF]

open access: yes, 2016
Despite the safety improvement drive that has been implemented in the construction industry in Singapore for many years, the industry continues to report the highest number of workplace fatalities, compared to other industries.
Kim, Hanjoon   +3 more
core   +3 more sources

Home - About - Disclaimer - Privacy