Results 81 to 90 of about 5,523,377 (316)

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Reasoned opinion on the modification of the existing MRLs for indoxacarb in beans (with pods) and mustard seed

EFSA Journal, 2013
In accordance with Article 6 of Regulation (EC) No 396/2005, the Netherlands, hereafter referred to as the evaluating Member State The Netherlands (EMS NL), received an application from the company LTO Groiservice to modify the existing MRLs for ...
European Food Safety Authority
doaj   +1 more source

Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol

New England Journal of Medicine, 2019
Background Short‐term studies have shown that bempedoic acid, an inhibitor of ATP citrate lyase, reduces levels of low‐density lipoprotein (LDL) cholesterol.
K. Ray, H. Bays, A. Catapano, N. Lalwani, L. Bloedon, L. Sterling, P. Robinson, C. Ballantyne   +7 more
semanticscholar   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Safety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment [PDF]

, 2021
Francesca Valdemarin, Irene Caffa, A Persia, Anna Laura Cremonini, Lorenzo Ferrando, Luca Tagliafico, Alberto Tagliafico, Ana Guijarro, Federico Carbone, Stefano Ministrini, Maria Bertolotto, Pamela Becherini, Tommaso Bonfiglio, Chiara Giannotti, A. Khalifa, Moustafa Ghanem, Michele Cea, Marzia Sucameli, Roberto Murialdo, Valentina Barbero, Raffaella Gradaschi, F. Bruzzone, Consuelo Borgarelli, Matteo Lambertini, Claudio Vernieri, Gabriele Zoppoli, Valter D. Longo, Fabrizio Montecucco, Samir Giuseppe Sukkar, Alessio Nencioni   +29 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Safety Evaluation of Yeasts With Probiotic Potential [PDF]

, 2021
Pilar Fernández‐Pacheco, Inés María Ramos, M. Fernández-González, Justa María Poveda, María Arévalo‐Villena   +4 more
openalex   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Evaluation of the application of Denmark to be recognised as having a negligible risk of classical scrapie

EFSA Journal, 2015
Denmark submitted a request to the European Commission to be recognised as a Member State with negligible risk of classical scrapie. EFSA has been asked to assess if Denmark in its application has demonstrated for a period of at least seven years ...
European Food Safety Authority
doaj   +1 more source

Machine learning models for classification tasks related to drug safety [PDF]

, 2021
Anita Rácz, Dávid Bajusz, Ramón Alain Miranda‐Quintana, Károly Héberger   +3 more
openalex   +1 more source