Results 61 to 70 of about 3,131,593 (360)
Increasing Nonlinear Behavior at the Soil-foundation Interface to Improve Seismic Performance of the Structure [PDF]
Numerical Methods in Civil EngineeringIt is well known that the performance of the structure is influenced by nonlinear behavior at the soil-foundation interface. Results of the previous studies have shown that the vertical Safety Factor (FS) of the foundation is not a suitable criterion to ...
Amir Hossein Jafarieh, Ahmadreza Hemmati
doaj +1 more source
XANTUS: rationale and design of a noninterventional study of rivaroxaban for the prevention of stroke in patients with atrial fibrillation. [PDF]
, 2014 Atrial fibrillation (AF) is associated with a fivefold increase in the risk of stroke. The Phase III ROCKET AF (Rivaroxaban Once-Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in ...
Amarenco, P +6 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Safety procedures of coagulation factors [PDF]
Haemophilia, 2007 Abstract Two main types of safety procedures must be applied to biological products, including plasma derivatives: (i) preventive procedures and (ii) elimination procedures.Prevention includes epidemiological control of donor populations; checks on each donor’s health condition; analysis of each donation for the main pathogens using serological ...
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
PATIENT SAFETY CULTURE AND ITS RELATED FACTORS FROM THE POINT OF VIEW OF NURSES WORKING IN HOSPITALS AFFILIATED TO BUSHEHR UNIVERSITY OF MEDICAL SCIENCES IN 2020 [PDF]
, 2023 Razieh Bagherzadeh +4 more
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Influence of Design Parameters of Anchor on Dyke Slope Stability
Renmin Zhujiang, 2021 Anchor is a commonly used supporting component in slope engineering,and its design parameters have a great influence on its anchoring effect.This paper studies the influence of length,spacing,inclination,anchoring area and anchoring length of anchors on ...
ZHENG Changhai +2 more
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