Results 151 to 160 of about 32,774 (244)

Population Pharmacokinetics and Exposure‐Response Analyses of Savolitinib Alone or in Combination With Osimertinib in Patients With Locally Advanced or Metastatic Solid Tumors

Clinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Savolitinib (ORPATHYS) is an oral, highly selective inhibitor of the mesenchymal–epithelial transition (MET) receptor tyrosine kinase that has demonstrated clinical activity across multiple advanced solid tumors. A comprehensive population pharmacokinetics analysis using cumulative data from 998 patients across 10 clinical studies ...
Azar Shahraz, Thibaud Derippe, Kiran Kumar Kode, Jessica Allmond, Simon Nelson, Ike Igwegbe, Aarti Sawant‐Basak, Karthick Vishwanathan, Kowser Miah   +8 more
wiley   +1 more source

Tempol Protects Against Radiation Injury in the Submandibular Gland Through the β‐Catenin Signaling Pathway

Journal of Oral Pathology &Medicine, Volume 55, Issue 8, Page 895-905, September 2026.
ABSTRACT Background Radiation damage severely impacts salivary gland function and cell survival, especially in head and neck radiotherapy. Tempol (TPL), a free radical scavenger, has shown protective effects against radiation damage. This research aimed to investigate the protective effects of TPL on radiation‐induced damage in Hs917.T cells and the ...
Jinfeng Wang, Mingjun Xu, Jinghua Zhong, Kui Zhong, Zheng Chen, Chunyu Liu, Chao Liu   +6 more
wiley   +1 more source

Dissecting the Role of Serotonin in Drought Responses of Rocket Plants: From Serotonin Accumulation to Tryptophan–ABA Associations

Physiologia Plantarum, Volume 178, Issue 5, September/October 2026.
ABSTRACT In recent years, serotonin has been proposed as a signaling molecule in several plant physiological processes, although evidence supporting this function remains limited to date. In particular, its involvement under water deficit conditions is poorly characterised, especially regarding its mechanism of action. This study aimed to determine the
Sofía Álvarez‐Real, Sergi Munné‐Bosch, Alba Arabia   +2 more
wiley   +1 more source

Unveiling the case of adulteration ini a commerical saffron sample

, 2015
In our previous study about the quality and authenticity of commercial saffron samples special attention was paid to the case of one sample that had been found suspicious for adulteration on the basis of UV-Vis and RP-HPLC-DAD data.
Cagliani Laura Ruth, Tsimidou Maria Z, Melidou Danfi, Kyriakoudi Anastasia, Stella A Ordoudi, Consonni Roberto   +5 more
core  

Integrated light spectrum and growth regulators improved the growth of saffron daughter corms by regulating carbohydrate metabolism in a novel two-stage cropping system. [PDF]

BMC Plant Biol
Eftekhari M, Javid MG, Gruda NS.
europepmc   +1 more source

Microbiological Quality of Commercial Enteral Formulas and Investigation of Antibacterial and Antioxidant Effects of Thyme, Saffron, and Turmeric Extract Mixture. [PDF]

Int J Prev Med
Sadeghzadeh R, Bagherniya M, Sami M.
europepmc   +1 more source

An efficient method for tissue-specific protoplast isolation suitable for single-cell RNA sequencing and transient gene expression analysis in saffron (Crocus sativus L.). [PDF]

BMC Biotechnol
Xi X, Song J, Feng M, Qian X, Sun H, Li L.   +5 more
europepmc   +1 more source

The effects of a saffron extract (Affron®) on mood, sleep, self-esteem, and exploratory measures of physical appearance in women aged 50 to 70 years experiencing low mood and poor sleep: a randomised, double-blind, placebo-controlled trial. [PDF]

Front Nutr
Lopresti AL, Smith SJ.
europepmc   +1 more source

Plant-derived bioactives in depression-related and antidepressant-associated sexual dysfunction: a narrative review. [PDF]

Front Nutr
Liu X, Sun Z, Gao J, Fu CY, Yang Z.
europepmc   +1 more source

Enhancement of Morpho-Physiological, Physiological, and Antioxidant Capacity of Saffron (<i>Crocus sativus</i> L.) Under Water Deficit Using ZnO Nanoparticles and Magnesium Sulfate: Implications for Saffron Yield. [PDF]

Food Sci Nutr
Fadala LT, Zaben S, Marir EMA, Meftahizade H.   +3 more
europepmc   +1 more source