Results 81 to 90 of about 2,346 (204)

Effects of Safranal on Tissue Oxidative Stress in Sub-Chronic Thinner-Addicted Rats

open access: yes, 2020
ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗThe present study was carried out to determine the effects of sub-chronic thinner addiction on the oxidant-antioxidant balance and oxidative stress on certain tissues and the possible protective effect of safranal against thinner ...
FIDAN, A. F., DÜZ, M.
core   +1 more source

Effects of Safranal on Lipopolysaccharide-Induced Acute Kidney Injury in C57BL/6 Mice [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Oxidative stress is a major contributor to kidney injury and plays a critical role in the pathogenesis of acute kidney injury (AKI) by promoting ischemia-reperfusion damage Experimental models of AKI often employ the induction of ...
Moein Farhang-Nasab   +3 more
doaj  

SIMULTANEOUS EXTRACTION AND RAPID HPLC BASED QUANTIFICATION OF CROCIN AND SAFRANAL IN SAFFRON (CROCUS SATIVUS L.)

open access: yes, 2016
Objective: Saffron (Crocus sativus L.) is one of the most valuable crops with high medicinal values used in many diseases. The aim of the study was to establish the reliability and rapid HPLC method for analysis of crocin and safranal concentration ...
Hosokawa, Munetaka   +4 more
core  

Therapeutic potential of safranal in acute bacterial rhinosinusitis: an experimental study

open access: yesThe Egyptian Journal of Otolaryngology
Background Safranal, a pharmacologically active and potent phytochemical, may exhibit significant antioxidant and anti-inflammatory activity in an acute bacterial rhinosinusitis.
Murat Yaşar   +6 more
doaj   +1 more source

Iron oxide nanoparticles coated with Glucose and conjugated with Safranal (Fe3O4@Glu-Safranal NPs) inducing apoptosis in liver cancer cell line (HepG2)

open access: yesBMC Chemistry
Magnetic nanoparticles can be considered a reliable tool for targeted drug delivery to cancer tissues. Based on this, in this study, the anticancer effect of iron oxide nanoparticles coated with glucose and conjugated with Safranal (Fe3O4@Glu-Safranal ...
Somayeh Mikaeili Ghezeljeh   +2 more
doaj   +1 more source

The Extract of Crocus sativus and Its Constituent Safranal, Affect Serum Levels of Endothelin and Total Protein in Sensitized Guinea Pigs [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2013
Objective(s): The effect of the extract of Crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   Materials and Methods: Ovalbumin (OA) sensitized guinea pigs were given drinking water alone (group ...
Zahra Gholamnezhad   +3 more
doaj  

Spectroscopic and Molecular Docking Investigation on the Noncovalent Interaction of Lysozyme with Saffron Constituent “Safranal”

open access: yes, 2020
Owing to the various beneficial properties of the popular spice saffron, the interaction of safranal, a secondary metabolite of the former, with hen egg white lysozyme was investigated. The formation of a complex was evidenced by UV–visible spectroscopy.
Mohd. Sajid Ali (8722818)   +1 more
core   +1 more source

Physicochemical Characterization of Safranal-β-Cyclodextrin Inclusion Complexes Prepared By Supercritical Carbon Dioxide and Conventional Methods.

open access: yes, 2013
Saffron (Crocus sativus. Linn) has attracted much attention over the last decade because it has a large number of potent and biologically active compounds such as crocin, crocetin, picrocrocin and safranal.
Abbaszadegan, Sanaz
core  

Protective Effect of Safranal, a Constituent of Crocus sativus, on Quinolinic Acid-induced Oxidative Damage in Rat Hippocampus [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2013
Objective(s): Quinolinic acid (QA)-mediated excitotoxicity has been widely used as a model for studying neurodegenerative disorders. Recent studies suggested that saffron (Crocus sativus) or its active metabolite, i.e.
Hamid Reza Sadeghnia   +4 more
doaj  

Effect of Crocus sativus extracts and its active constituent safranal on the harmaline-induced tremor in mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2015
Objective(s): Due to unsatisfactory response or intolerable side effects of current drugs, treatment of essential tremor remains inadequate. Thus, we aimed to investigate the protective and therapeutic effects of aqueous and ethanolic extracts of Crocus ...
Bahareh Amin   +3 more
doaj  

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