Results 81 to 90 of about 26,304 (229)

Phenol Neurolysis in Pain and Palliative Medicine

Pain Practice, Volume 26, Issue 5, June 2026.
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Jeroen H. A. Creemers, Rachel J. H. Smits, Alopi M. Patel, Robert T. M. van Dongen, Cornelis K. Kramers, Jacqueline M. Bos, Selina E. I. van der Wal   +6 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Colorectal endoscopic mucosal resection with submucosal injection of epinephrine versus hypertonic saline in patients taking antithrombotic agents: propensity-score-matching analysis

BMC Gastroenterology, 2019
Background Endoscopic mucosal resection (EMR) to remove colon polyps is increasingly common in patients taking antithrombotic agents. The safety of EMR with submucosal saline injection has not been clearly demonstrated in this population.
Daisuke Yamaguchi, Hisako Yoshida, Kei Ikeda, Yuki Takeuchi, Shota Yamashita, Amane Jubashi, Takahiro Yukimoto, Eri Takeshita, Wataru Yoshioka, Hiroko Fukuda, Naoyuki Tominaga, Nanae Tsuruoka, Tomohito Morisaki, Keisuke Ario, Seiji Tsunada, Kazuma Fujimoto   +15 more
doaj   +1 more source

The relation between the incidence of hypernatremia and mortality in patients with severe traumatic brain injury [PDF]

, 2009
INTRODUCTION: The study was aimed at verifying whether the occurrence of hypernatremia during the intensive care unit (ICU) stay increases the risk of death in patients with severe traumatic brain injury (TBI).
Umberto Maggiore, Edoardo Picetti, Elio Antonucci, Elisabetta Parenti, Giuseppe Regolisti, Mario Mergoni, Antonella Vezzani, Aderville Cabassi, Enrico Fiaccadori   +8 more
core   +1 more source

Pancreatic Cancer—Advances in the Last 50 Years

World Journal of Surgery, EarlyView.
S. George Barreto, Anirban Maitra, Eileen M. O'Reilly, Dushyant Sahani, Richard Zheng, Charles J. Yeo   +5 more
wiley   +1 more source

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
The incubation of primary astrocytes with fAuNCs‐BSA induces: (A) long‐term effects including fAuNCs‐BSA internalization, red cell fluorescence, differentiation, upregulation of Ca2+ signaling, Cl‐current, and cell volume regulation. B) Short‐term (200 ms) stimulation with UV LED light increases in Ca2+ signaling and inhibition of K+ current. Astrocyte
Roberta Fabbri, Karima Jeneh Perry, Emanuela Saracino, Chiara Lazzarini, Anna Mariano, Diletta Spennato, Maria Grazia Mola, Maria Grazia Raucci, Alessandro Kovtun, Marianna Barbalinardo, Giorgia Conte, Denis Gentili, Marco Caprini, Vincenzo Palermo, Roberto Zamboni, Luigi Ambrosio, Wolfgang Losert, Andrea Candini, Grazia Paola Nicchia, Raj K. Gupta, Valentina Benfenati, Shashi P. Karna   +21 more
wiley   +1 more source

Therapeutic effects of Ventolin versus hypertonic saline 3% for acute bronchiolitis in children. [PDF]

, 2015
BACKGROUND Complications of Ventolin as the most common drug used for bronchiolitis are widely known. The present study was conducted to determine the efficacy of hypertonic saline 3%, compared with Ventolin, for treatment of acute bronchiolitis in ...
Etemadifar, Shahram., Ganji, Forouzan., Keivani Hafshejani, zahra., Khoshdel, Abolfazl., Mobasheri, Mahmoud., Movahhedi, Mehran., Nourbakhsh, Seyyed Mohammad-Kazem., Rafieian-Kopaei, Mahmoud., Shirani, Majid., Zamani, Mohammad Ali.   +9 more
core   +1 more source

An Atypical Presentation of Tuberculous Ascites, Severe Hyponatremia, and Acute Kidney Injury in a Young Male

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A 25‐year‐old male who had been in good health before presenting with right lower lobe pneumonia, severe hyponatremia (Na 117 mEq/L), distension, and reduced urine output. AKI secondary to acute glomerulonephritis (GN) or interstitial nephritis was suggested by the initial workup. He was discharged for outpatient nephrology follow‐up following
Bassem Al Hariri, Muhammad Sharif, Memon Noor Illahi, Asgad Mohamed Ahmed Eltigani, Usamah Saad Mohammad Al Anbagi, Muayad Ahmad   +5 more
wiley   +1 more source

The role of the vagus nerve in hypertonic resuscitation of hemorrhagic shocked dogs

Brazilian Journal of Medical and Biological Research, 2004
Previous studies have suggested a critical role for the vagi during the hypertonic resuscitation of hemorrhagic shocked dogs. Vagal blockade prevented the full hemodynamic and metabolic recovery and increased mortality.
I.T. Velasco, R.C. Baena
doaj   +1 more source

Intra-Arterial Hypertonic Saline Solution in Experimental Shock

Experimental Biology and Medicine, 1939
ConclusionsThe findings of Davis and coworkers on the effect of administering a concentrated solution of sodium chloride have been corroborated. However, it seems apparent from our observations that the intra-arterial administration of 25% saline solution cannot be recommended as an emergency treatment for secondary shock.
D. B. Kendrick, K. G. Wakim
openaire   +1 more source