Results 101 to 110 of about 7,383 (256)
Synthetic modification of salinomycin: selective O-acylation and biological evaluation
, 2013 Salinomycin has found renewed interest as an agent for prevention of cancer recurrence through selectively targeting cancer stem cells. Strategies for generation of improved salinomycin analogs by individual modification of its hydroxyl groups are ...
Borgström, Björn +5 more
core +1 more source
Antimicrobial prescribing guidelines for feedlot cattle
Australian Veterinary Journal, Volume 104, Issue 7, Page 413-438, July 2026.
P Cusack +4 more
wiley +1 more source
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Protein Science, Volume 35, Issue 3, March 2026.Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source
Salinomycin suppresses STAT3 activation.
, 2015 (A) Basal levels of STAT3 and phospho-STAT3 (Tyr705) in seven breast cancer cell lines: luminal-type (MCF7 and T47D), HER2-amplified (BT474, MDA-MB-453, and SKBR3), and TNBC (Hs578T and MDA-MB-231).
Ji Young Kim (171004) +5 more
core +1 more source
, 2020 Background: Salinomycin, an ionophore antibiotic, is known to be an effective agent in reducing the viability of Glioblastoma (GBM) cells. The combination of salinomycin with other chemotherapeutic drugs would help to overcome the drug resistance of GBM ...
Gunduz, C. +5 more
core +2 more sources
Small Structures, Volume 7, Issue 3, March 2026.Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
, 2017 Jun Li,1,* Wenqing Xu,2,* Xiaoli Yuan,3,* Huaiwen Chen,3 Hao Song,1,4 Bingquan Wang,5 Jun Han5 1College of Pharmacy, Liaocheng University, Liaocheng, Shandong, 2Railway Police College, Zhengzhou, 3Department of Cadre Health Care, Nanjing General ...
Xu WQ +6 more
core
Advanced Science, Volume 13, Issue 12, 27 February 2026.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
Induction of reactive oxygen species by salinomycin treatment.
, 2012 Production of ROS was measured by flow cytometry in RKO, MCF-7 and SW620 cells 30 hours after treatment with the indicated concentrations of salinomycin or solvent control. Treatment with 1 mM H2O2 for 1 hour served as a positive control.
Inge Schmitz (134566) +5 more
core +1 more source
Exploration, Volume 6, Issue 1, February 2026.ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao +10 more
wiley +1 more source