Results 81 to 90 of about 5,454 (214)
British Journal of Haematology, Volume 208, Issue 5, Page 1572-1583, May 2026.Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika +4 more
wiley +1 more source
Induction of reactive oxygen species by salinomycin treatment.
, 2012 Production of ROS was measured by flow cytometry in RKO, MCF-7 and SW620 cells 30 hours after treatment with the indicated concentrations of salinomycin or solvent control. Treatment with 1 mM H2O2 for 1 hour served as a positive control.
Inge Schmitz (134566) +5 more
core +1 more source
Matrifibrocytes Redefine Cardiac Fibrosis: From Terminal Differentiation to Translational Modulation
Journal of Cellular and Molecular Medicine, Volume 30, Issue 10, May 2026.ABSTRACT Cardiac fibrosis is increasingly recognized as a dynamic program that resolves into a terminal fibroblast fate, the matrifibrocyte, rather than a persistent myofibroblast state. Lineage‐tracing and single‐cell studies reveal that matrifibrocytes arise from activated myofibroblasts during late scar maturation, lose α‐SMA and proliferative ...
Zhentao Zhang, Hua Zhu
wiley +1 more source
Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity : Differences between primary and cancer cells [PDF]
, 2013 The molecular mechanism of Salinomycin's toxicity is not fully understood. Various studies reported that Ca2 +, cytochrome c, and caspase activation play a role in Salinomycin-induced cytotoxicity.
Ghavami, Saeid +22 more
core +1 more source
Salinomycin inhibits tumor growth in a patient-derived xenograft model.
, 2019 (A) Subcutaneous colorectal cancer growth in NOD/SCID-IL2RGnull mice was induced through injection of TICs into the right flank of the animals. After tumor growth, treatment with either vehicle, salinomycin, or FOLFOX regimen (5-fluorouracil, calcium ...
Arsalie Preißendörfer Charrier (6335654) +12 more
core +1 more source
Mass spectrometry data for the paper 'High-Resolution Electrospray and Ion Mobility Sequential Mass Spectrometry for Structural Characterisation of Anticancer Stem Cell Agent Salinomycin and Its Isomers'
Jiang, Candy, Gates, Paul
core +1 more source
Salinomycin induces autophagy in osteoblastoma cells.
, 2013 Cultured U2OS osteoblastoma cells were treated with vehicle (0.1 % of DMSO), indicated concentration of salinomycin (Sali) or salinomycin (10 μM) plus 3-methyladenine (3-MA, 1 mM) for 24 hours, LC3B puncta fluorescence was detected by the confocal ...
Zhi-xiong Guo (498738) +5 more
core +1 more source
Salinomycin, a new polyether antibiotic.
The Journal of Antibiotics, 1974 Salinomycin is a new polyether antibiotic produced by a strain of Streptomyces albus (ATCC 21838). The antibiotic is purified by solvent extraction followed by chromatography on alumina or silica gel. It is a weakly acidic compound and has the molecular formula C42H70O11.
YUKIO MIYAZAKI +6 more
openaire +3 more sources
Autophagy inhibition enhances salinomycin-induced cytotoxicity in osteoblastoma cells.
, 2013 U2OS cells were treated with indicated concentration of salinomycin (Sali, 0.1, 1, 5 and 10 μM) for 48 hours (A), or treated with 10 μM of salinomycin for indicated time (B), cell viability was analyzed by CCK-8 cell viability assay. U2OS and MG-63 cells
Zhi-xiong Guo (498738) +5 more
core +1 more source
BMC Veterinary ResearchBackground Salinomycin, an antibiotic, have potential as a veterinary drug for fish due to its anti-parasitic activity against several fish parasites.
Seungjin Lee +9 more
doaj +1 more source