Results 61 to 70 of about 3,796 (173)
PLoS ONE, 2014 Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells.
Johannes Klose +10 more
doaj +1 more source
Heterocyclic‐Fused Squaramides: Anionophores With Antimicrobial Activity
ChemBioChem, Volume 27, Issue 5, 13 March 2026.Supramolecular medicinal chemistry has allowed for the development of novel drugs for the treatment of cystic fibrosis, and in the fight against cancer. However, little has been done to develop these as antimicrobial agents. Here, we describe the development of novel chemical tools to further develop supramolecular methods to combat the global plight ...
Luke Edward Brennan +3 more
wiley +1 more source
Salinomycin triggers endoplasmic reticulum stress through ATP2A3 upregulation in PC-3 cells
BMC Cancer, 2019 Background Salinomycin is a monocarboxylic polyether antibiotic and is a potential chemotherapy drug. Our previous studies showed that salinomycin inhibited cell growth and targeted CSCs in prostate cancer.
Yunsheng Zhang +8 more
doaj +1 more source
Antimicrobial prescribing guidelines for feedlot cattle
Australian Veterinary Journal, Volume 104, Issue 7, Page 413-438, July 2026.
P Cusack +4 more
wiley +1 more source
Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang +6 more
wiley +1 more source
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Protein Science, Volume 35, Issue 3, March 2026.Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source
Small Structures, Volume 7, Issue 3, March 2026.Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
Advanced Science, Volume 13, Issue 12, 27 February 2026.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
Salinomycin, a new polyether antibiotic.
The Journal of Antibiotics, 1974 Salinomycin is a new polyether antibiotic produced by a strain of Streptomyces albus (ATCC 21838). The antibiotic is purified by solvent extraction followed by chromatography on alumina or silica gel. It is a weakly acidic compound and has the molecular formula C42H70O11.
YUKIO MIYAZAKI +6 more
openaire +3 more sources
BMC Veterinary ResearchBackground Salinomycin, an antibiotic, have potential as a veterinary drug for fish due to its anti-parasitic activity against several fish parasites.
Seungjin Lee +9 more
doaj +1 more source