Results 61 to 70 of about 7,383 (256)

CSC+Salinomycin

, 2019
Salinomycin reduced CSCs on the cell spheroids and made it difficult to start ...
Quan (7042298)
core   +1 more source

Effect of salinomycin on TRAIL-R2 expression.

, 2014
(A)Flow cytometric analysis of TRAIL-R2 expression of T98G and U251 cells grown for 24 h in the absence (NT) or in the presence of 10 µM salinomycin (Sal).
Lucia Ricci-Vitiani (268795), Ernestina Saulle (168702), Maria Laura De Angelis (552887), Ugo Testa (168771), Luca Pasquini (168695), Federica Pelacchi (552889), Alessia Calzolari (552886), Alessandra Boe (552888), Marta Baiocchi (552890)   +8 more
core   +1 more source

Evaluation of ionophore resistance in field isolates of Eimeria tenella from Jammu and Kashmir

Indian Journal of Animal Sciences, 2023
The present study was conducted to evaluate resistance against ionophores (salinomycin and maduramicin) in four field isolates (F) of Eimeria tenella collected from four distantly located poultry farms from Union territory of Jammu and Kashmir.
AIMAN KHURSHEED, ANISH YADAV, VIKAS YADAV, OMER M SOFI, ANAND KUSHWAHA, SHAFIYA I RAFIQI, RAJESH GODARA, SHILPA SOOD, DIBYENDU CHAKRABORTY, RAJESH KATOCH   +9 more
doaj   +1 more source

Metal‐dependent regulated cell death: Molecular architecture and translational frontiers

iMeta, EarlyView.
Intracellular metal dyshomeostasis orchestrates distinct regulated cell death programs, including iron‐driven ferroptosis, copper‐mediated cuproptosis, calcicoptosis, newly designated zincoptosis, mnoptosis, and coptosis. This review systematically delineates their molecular architectures—spanning from Sorafenib‐induced lipid peroxidation and ...
Haoliang Hu, Zhe Chen, Yaqi Li, Jiayi Peng, Jiangang Cao, Hong Zhou, Mengqi Wang, Yuejia Du, Hailin Wu, Huiqin Zhao, Shifang Huang, Dianmei Yu, Meiqing Liu, Olga V. Shevchenko, Natalia Yu. Matveeva, Yiyuan Yang, Kerui Huang, Deguan Lv, Junxia Min, Linxi Chen, Fudi Wang   +20 more
wiley   +1 more source

Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells.

PLoS ONE, 2015
Triple-negative breast cancer (TNBC) is an aggressive tumor subtype with an enriched CD44+/CD24- stem-like population. Salinomycin is an antibiotic that has been shown to target cancer stem cells (CSC); however, the mechanisms of action involved have not
Hyunsook An, Ji Young Kim, Eunhye Oh, Nahyun Lee, Youngkwan Cho, Jae Hong Seo   +5 more
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Comparative Transcriptome-Based Mining of Genes Involved in the Export of Polyether Antibiotics for Titer Improvement

Antibiotics, 2022
The anti-coccidiosis agent salinomycin is a polyether antibiotic produced by Streptomyces albus BK3-25 with a remarkable titer of 18 g/L at flask scale, suggesting a highly efficient export system.
Xian Liu, Yuanting Wu, Xiaojie Zhang, Qianjin Kang, Yusi Yan, Linquan Bai   +5 more
doaj   +1 more source

Efficacy and Growth Performance between Two Different Ionophore Coccidiostats (Narasin and Salinomycin) in Broiler Chickens after Challenge with Eimeria spp.

Animals
Simple Summary There has been an exponential increase in demand for poultry meat and eggs worldwide. Therefore, it is essential to keep coccidiosis under control in broilers to fulfill the increase in demand for protein.
Monika Rogala-Hnatowska, George Gould, Shubhi Mehrotra, A. Drażbo, P. Konieczka, P. Ramasami, K. Kozłowski   +6 more
semanticscholar   +1 more source

Salinomycin biosynthesis reversely regulates the β‐oxidation pathway in Streptomyces albus by carrying a 3‐hydroxyacyl‐CoA dehydrogenase gene in its biosynthetic gene cluster

Microbial Biotechnology, 2022
Streptomyces is well known for synthesis of many biologically active secondary metabolites, such as polyketides and non‐ribosomal peptides. Understanding the coupling mechanisms of primary and secondary metabolism can help develop strategies to improve ...
Jiaxiu Wei, Binbin Chen, Jianxin Dong, Xueyu Wang, Yongquan Li, Y. Liu, W. Guan   +6 more
semanticscholar   +1 more source

Salinomycin impairs HCC cell survival.

, 2014
HepG2 and Huh7 cells were exposed to increasing concentrations of Salinomycin (1, 2, 5 and 10 µM) for 24 hours. (A) Cell viability was assessed by MTS-assay; high concentrations of Salinomycin led to significantly decreased viability of both cell lines ...
Georg M. N. Behrens (562058), Hüseyin Bektas (562057), Florian W. R. Vondran (476274), Wolf Ramackers (562053), Mark D. Jäger (562055), Michael Winkler (119116), Metodi V. Stankov (562051), Moritz Kleine (562052), Johannes Klose (562050), Jürgen Klempnauer (562056), Diana Panayotova-Dimitrova (562054)   +10 more
core   +1 more source