Results 61 to 70 of about 5,454 (214)
A major challenge for oncologists and pharmacologists is to develop more potent and less toxic drugs that will decrease the tumor growth and improve the survival of lung cancer patients.
Kholoud Arafat +6 more
doaj +1 more source
Unfavorable alterations of the commensal gut microbiota and dysbacteriosis is a major health problem in the poultry industry. Understanding how dietary intervention alters the microbial ecology of broiler chickens is important for prevention strategies ...
Mohammad Naghizadeh +5 more
doaj +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Activation of the JNK pathway by salinomycin.
(A) Exposure to 2.5 µM salinomycin induced the expression and activation of JNK, as well as its target JUN in MCF-7 cells. (B) Increased JNK kinase activity after salinomycin treatment in MCF-7. The JNK kinase assay was carried out after treatment with 2.
Inge Schmitz (134566) +5 more
core +1 more source
Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been reported to exhibit therapeutic activity in cancer. However, many tumors remain resistant to treatment with TRAIL.
Alessia Calzolari +8 more
doaj +1 more source
Abstract INTRODUCTION Dementia is a public health challenge and exposures likely contribute to risk, though many have not been evaluated. We screened chemicals for enrichment with dementia genes and related pathways. METHODS We obtained gene lists from Agora and the Comparative Toxicogenomics Database (CTD) for 1008 chemicals and nine dementia‐related ...
Scarlet Cockell +5 more
wiley +1 more source
Effects of Dietary Lactiplantibacillus pentosus and Salinomycin on Growth Performance, Meat Quality, Antioxidant Status, and Serum Parameters in Broilers Fed Diets Differing in Nutrient Density [PDF]
The study aimed to evaluate dietary Lactiplantibacillus pentosus [LP]-based probiotic as an alternative to in-feed antibiotics for broilers fed diets containing different nutrient densities.
VA Vu +6 more
doaj +2 more sources
This paper aims to address critical gaps in the literature by providing a comprehensive, integrative synthesis of recent advances in Streptomyces strain improvement, with a particular focus on optimizing secondary metabolite production through a multidisciplinary approach.
Anum Goraya +5 more
wiley +1 more source
Influence of Salinomycin on the Performance of Broiler Chicks
Two experiments were conducted to determine the influence of graded levels of salinomycin on the performance of broiler chicks. Cobb feather-sexed chicks were fed experimental diets from 1 to 21 days of age. A significant depression in body weight and feed consumption was obtained when the feed contained 77 ppm of salinomycin.
R H, Harms, R E, Buresh
openaire +2 more sources
Natural Products as Modulators of ABC Transporters in Breast Cancer
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source

