Results 51 to 60 of about 5,454 (214)
Salinomycin suppresses cell viability.
, 2015 TNBC cell lines [(A) MDA-MB-231 and (B) 4T1 cells] were treated with salinomycin (0.5–10 μM) or vehicle (DMSO) for the indicated durations. Viable cells were evaluated by MTS assay.
Ji Young Kim (171004) +5 more
core +1 more source
The F204S mutation in adrenodoxin oxidoreductase drives salinomycin resistance in Eimeria tenella
Veterinary ResearchSalinomycin is a polyether ionophore widely used for the treatment of coccidiosis in poultry. However, the emergence of coccidia strains resistant to salinomycin presents challenges for control efforts, and the mechanisms underlying this resistance in ...
Pei Sun +13 more
doaj +1 more source
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Andrology, EarlyView.Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
Salinomycin induces anoikis-sensitivity.
, 2015 (A) After exposure to salinomycin (0.5–2 μM) or DMSO for 24–48 h, the sub-G1 population was examined by flow cytometry. The percentage of cells in the sub-G1 fraction (red arrow) is depicted in the plot. (B-D) MDA-MB-231 and (E-F) 4T1 cells were grown in
Ji Young Kim (171004) +5 more
core +1 more source
Anticancer Mechanisms of Salinomycin in Breast Cancer and Its Clinical Applications
Frontiers in Oncology, 2021 Breast cancer (BC) is the most frequent cancer among women worldwide and is the leading cause of cancer-related deaths in women. Cancer cells with stem cell-like features and tumor-initiating potential contribute to drug resistance, tumor recurrence, and
Hui Wang +7 more
doaj +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Ist Salinomycin ein Radiosensitizer für Plattenepithelkarzinomzellen in vitro?
, 2017 Einleitung: Eine Bestrahlung ist bei vielen HNO-Tumorentitäten Bestandteil der Therapieregime. Aktuell wird simultan zur Bestrahlung vor allem Cisplatin aufgrund seiner radiosensibilisierenden Eigenschaften eingesetzt.
Kleinsasser, N +3 more
core +1 more source
Effect of a mixture of monoglycerides with salinomycin on the growth performance and intestine morphology in broiler chickens [PDF]
BIO Web of ConferencesThis study aims to interact with the combined influence of monoglyceride supplementation and salinomycin on growth performance and the morphology of the small intestine in broiler chickens.
Siriphong Hutsanai +4 more
doaj +1 more source
Nano Select, Volume 7, Issue 10, October 2026.Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei +3 more
wiley +1 more source
MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source