Results 71 to 80 of about 7,383 (256)
Salinomycin decreases feline sarcoma and carcinoma cell viability when combined with doxorubicin
BMC Veterinary Research, 2019 Background Cancer is a significant health threat in cats. Chemoresistance is prevalent in solid tumors. The ionophore salinomycin has anti-cancer properties and may work synergistically with chemotherapeutics. The purpose of our study was to determine if
Lucia Borlle +5 more
doaj +1 more source
Salinomycin Derivatives Kill Breast Cancer Stem Cells via Lysosomal Iron Targeting.
Chemistry, 2020 Salinomycin ( 1 ) exhibits a large spectrum of biological activities including the capacity to selectively eradicate cancer stem cells (CSC), making it and its derivatives promising candidates for the development of drug leads against CSC.
A. Versini +8 more
semanticscholar +1 more source
Reports of Biochemistry and Molecular Biology, 2022 Background Prostate cancer is known as one of the most prevalent health disorders in the male population globally. The aim of the current study was to evaluate the effects of separate and concomitant use of MK-2206 and salinomycin on prostate cancer cell
Mohamadreza Savaee +4 more
semanticscholar +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Salinomycin suppresses cell viability.
, 2015 TNBC cell lines [(A) MDA-MB-231 and (B) 4T1 cells] were treated with salinomycin (0.5–10 μM) or vehicle (DMSO) for the indicated durations. Viable cells were evaluated by MTS assay.
Ji Young Kim (171004) +5 more
core +1 more source
Effect of a mixture of monoglycerides with salinomycin on the growth performance and intestine morphology in broiler chickens [PDF]
BIO Web of ConferencesThis study aims to interact with the combined influence of monoglyceride supplementation and salinomycin on growth performance and the morphology of the small intestine in broiler chickens.
Siriphong Hutsanai +4 more
doaj +1 more source
Salinomycin-Based Drug Delivery Systems: Overcoming the Hurdles in Cancer Therapy
Pharmaceutics, 2021 Cancer stem cells (CSCs) are reportedly responsible for the initiation and propagation of cancer. Since CSCs are highly resistant to conventional chemo- and radiotherapy, they are considered the main cause of cancer relapse and metastasis.
L. Tefas +3 more
semanticscholar +1 more source
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Salinomycin induces anoikis-sensitivity.
, 2015 (A) After exposure to salinomycin (0.5–2 μM) or DMSO for 24–48 h, the sub-G1 population was examined by flow cytometry. The percentage of cells in the sub-G1 fraction (red arrow) is depicted in the plot. (B-D) MDA-MB-231 and (E-F) 4T1 cells were grown in
Ji Young Kim (171004) +5 more
core +1 more source
Journal of Animal Science, 2021 The aim of the present study was to evaluate the inclusion of narasin, salinomycin, or flavomycin for 140 d on ruminal fermentation parameters, apparent nutrient digestibility, and performance of Nellore cattle offered a forage-based diet.
A. Limede +9 more
semanticscholar +1 more source