Results 31 to 40 of about 34,824 (270)

Exosomes and their roles in the chemoresistance of pancreatic cancer

Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022
Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan, Honglin Tang, Qijun Li, Guangpeng Chen, Da Li   +4 more
wiley   +1 more source

Concordance of breast cancer biomarker testing in core needle biopsy and surgical specimens: A single institution experience

Cancer Medicine, Volume 11, Issue 24, Page 4954-4965, December 2022., 2022
Retesting estrogen receptor and HER2 status provides more clinical benefit than retesting progesterone receptor status. We propose guidelines for retesting receptor profiles to aid patient care management decisions, prioritize clinical benefits, and minimize healthcare costs.
Jessica A. Slostad, Nicole K. Yun, Aimee E. Schad, Surbhi Warrior, Louis F. Fogg, Ruta Rao   +5 more
wiley   +1 more source

Brain-derived neurotrophic factor is related to stress and chewing in saliva and salivary glands

Japanese Dental Science Review, 2020
Summary: Chewing is one of the most important orofacial functions. During this process, food is reduced in size, while saliva moistens the food and binds it into a bolus that can be easily swallowed.
Juri Saruta, Masahiro To, Wakako Sakaguchi, Yusuke Kondo, Keiichi Tsukinoki   +4 more
doaj  

The activity of selected glycosidases in salivary gland tumors.

Folia Histochemica et Cytobiologica, 2010
The monitoring of the patients after salivary gland tumors surgery is an important clinical issue. Still imperfect diagnostic procedures also remain a challenge for searching new sensitive and specific biomarkers of neoplastic processes in salivary ...
Sylwia Chojnowska, Lukasz Woźniak, Lukasz Minarowski, Marcin Bierc, Malgorzata Knas, Slawomir Szajda, Krzysztof Zwierz   +6 more
doaj   +1 more source

Pleomorphic adenoma of buccal minor salivary gland: A case report

Journal of Craniomaxillofacial Research, 2023
Pleomorphic adenoma is a benign salivary gland tumor that is frequently seen in the parotid gland. It is very rare in minor salivary glands. The case we present is a case of pleomorphic adenoma originating from the buccal minor salivary gland, which ...
Melike Baygin Durak, Mustafa Mert Açikgöz, Banu Gürkan Köseoğlu   +2 more
doaj  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Submandibular Sialolithiasis in a 9-year-old child: case report [PDF]

arXiv, 2023
Sialolithiasis rarely occurs in children; it is observed more commonly in adults. Various treatment modalities for sialolithiasis have been reported in literature; we report the case of 9 years old child, with no particular pathological history. For 4 years, he had a tumefaction of the left submandibular region, associated with painful blocking ...
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Dynamic relationship of the epithelium and mesenchyme during salivary gland initiation: the role of Fgf10

Biology Open, 2013
Summary Salivary glands provide an excellent model for the study of epithelial–mesenchymal interactions. We have looked at the interactions involved in the early initiation and development of murine salivary glands using classic recombination experiments
Kirsty L. Wells, Marcia Gaete, Eva Matalova, Danny Deutsch, David Rice, Abigail S. Tucker   +5 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source