Results 131 to 140 of about 143,429 (278)

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

gnSPADE: Incorporating Gene Network Structures Enhances Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Intelligent Systems, EarlyView.
gnSPADE integrates gene‐network structures into a probabilistic topic modeling framework to achieve reference‐free cell‐type deconvolution in spatial transcriptomics. By embedding gene connectivity within the generative process, gnSPADE enhances biological interpretability and accuracy across simulated and real datasets, revealing spatial organization ...
Aoqi Xie, Yuehua Cui
wiley   +1 more source

Salivary Glands Proteins Expression of Anopheles dirus A Fed on Plasmodium vivax- and Plasmodium falciparum-Infected Human Blood

Journal of Parasitology Research, 2013
Mosquitoes are able to adapt to feed on blood by the salivary glands which created a protein that works against the haemostasis process. This study aims to investigate the salivary glands proteins expression of 50 adult female An.
Saowanee Cotama, Paron Dekumyoy, Yudthana Samung, Usa Lek-Uthai   +3 more
doaj   +1 more source

Diverse Genetic Etiologies of Unilateral Polymicrogyria

Annals of Neurology, EarlyView.
Objective Polymicrogyria (PMG) is one of the most common human malformations of cortical development and is often classified by its radiographic pattern of distribution. Unilateral polymicrogyria (uPMG) is a subtype of PMG affecting a portion or all of one cerebral hemisphere.
Abbe Lai, Jennifer E. Neil, Shyam K. Akula, Dina Amrom, Eva Andermann, Ann Bergin, Roberto Caraballo, Allen Y. Chen, John Gaitanis, Ganeshwaran H. Mochida, Jill M. Gotoff, Giorgi Kuchukhidze, Daphna Marom, Christelle Moufawad ElAchkar, Miriam Regev, Lance H. Rodan, Heather Olson, Bo Zhang, Annapurna Poduri, Diane D. Shao, Christopher A. Walsh, Edward Yang   +21 more
wiley   +1 more source

The Effect of Silk on the Stabilization of Labile Enzyme Lipoxygenase

Advanced NanoBiomed Research, EarlyView.
Entrapping lipoxygenase within silk significantly extended its stability from under 24 h to 10 days. Variations in silk molecular weight and freeze‐drying conditions influenced silk properties and enzyme interactions. This stabilization is leveraged to develop a linoleic acid electrochemical biosensor, integrating lipoxygenase with horseradish ...
Jacopo Giaretta, Xinyu (Vivian) Xie, Sandra Spoa, Hien A. Tran, Syamak Farajikhah, Sepehr Talebian, Jelena Rnjak‐Kovacina, Fariba Dehghani   +7 more
wiley   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

Advanced NanoBiomed Research, EarlyView.
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang, Ying Zhi Cheong, Chenglong Xu, Sanje Mahasivam, Xudong Cai, Vipul Bansal, Sharath Sriram, Ganganath Perera, Madhu Bhaskaran   +8 more
wiley   +1 more source

Identification of Potential Amblyomma americanum Antigens After Vaccination with Tick Extracellular Vesicles in White-Tailed Deer

Vaccines
Background/Objective: Anti-tick vaccines represent a promising alternative to chemical acaricides for the management of ticks on wildlife; however, little progress has been made to produce a vaccine effective in wild hosts that are critical for tick ...
Adela Oliva Chávez, Julia Gonzalez, Cristina Harvey, Cárita de Souza Ribeiro-Silva, Brenda Leal-Galvan, Kelly A. Persinger, Sarah Durski, Pia U. Olafson, Tammi L. Johnson   +8 more
doaj   +1 more source

Radium Speciation in Simulated Digestive Biofluids: Insights from Electrospray Ionization Mass Spectrometry and Thermodynamic Modeling

Analysis &Sensing, EarlyView.
Electrospray ionization mass spectrometry (ESI‐MS) combined with thermodynamic modeling provides the first direct characterization of radium speciation in synthetic gastrointestinal biofluids. Free Ra2+ ions predominate with minimal protein binding and negligible EDTA complexation. Crown ethers enable effective Ra complexation.
Linus Holtmann, Tim Schmalz, Tobias Weissenborn, Felix Stäger, Beate Riebe, Clemens Walther   +5 more
wiley   +1 more source

Effects of Replacing Alfalfa Hay With Barley Silage in High‐Concentrate Diets: Chewing Behavior, Ruminal Fermentation, Total‐Tract Digestibility, and Milk Production of Dairy Cows in Mid‐Lactation Phase

Animal Research and One Health, EarlyView.
We assessed lactation productivity in dairy cows when replacing alfalfa hay with barley silage. A 50% replacement increased feed intake, whereas total replacement improved nutrient conversion to milk. Barley silage can effectively replace alfalfa hay, enhancing sustainability and resilience in dairy production amid forage quality constraints and market
M. R. Naji‐Zavareh, F. Hashemzadeh, M. Alikhani, M. Khorvash, A. Kahyani, F. Ahmadi   +5 more
wiley   +1 more source