Results 41 to 50 of about 20,380 (190)

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Genotyping of Salmonella Enterica Serovar Enteritidis Strains Isolated from Clinical Samples by Pulsed-Field Gel Electrophoresis (PFGE)

مجله دانشکده پزشکی اصفهان, 2013
Background: The infections caused by Salmonella enterica serovar enteritidis (Salmonella enteritidis) have been increasing in developed and developing countries.
Zeinab Ahmadi, Reza Ranjbar, Meysam Sarshar   +2 more
doaj  

The study of drug resistance characteristics and molecular typing of Salmonella enteritidis in Lanzhou City from 2019 to 2021

Zhongguo shipin weisheng zazhi
ObjectiveTo provide scientific value for effective prevention of Salmonella infection and treatment， the drug resistance spectrum and drug resistance characteristics of Salmonella enteritidis in Lanzhou was exploreed and a database of some genotypes of ...
MAO Xue, ZHANG Lianmei, WANG Yuhong, WANG Yan, CHENG Hui, ZHANG Jijun, DI Mengjie, LIU Lu   +7 more
doaj   +1 more source

SIMPLEKS DAN MULTIPLEKS PRE-ENRICHMENT-PCR UNTUK DETEKSI Salmonella Enteritidis DAN Typhimurium PADA KARKAS AYAM

Jurnal Teknologi dan Industri Pangan, 2021
A PCR assay has been developed and applied to detect Salmonella contamination in chicken carcasses. However, a concentration fewer than 3 cells per gram lead to false-negative results due to difficulties in the DNA extraction. The objective of this study
Siti Nurjanah, Winiati P. Rahayu, Ratih Dewanti-Hariyadi, Ni Gusti Ayu Made Widyatari Asthiti, Rahadina Praba Melati   +4 more
doaj   +1 more source

Simultaneous modification of Thermotoga maritima encapsulin subunits to produce multivalent nanoparticle vaccines for non‐typhoidal Salmonella enterica

The FEBS Journal, EarlyView.
This study investigates the modularity of encapsulin—a protein nanoparticle—by simultaneously inserting up to four distinct Salmonella epitopes within the encapsulin subunit. The encapsulin variants were transiently expressed in plants where they assembled into nanoparticles; however, their accumulation and stability varied depending on the ...
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +5 more
wiley   +1 more source

A spatiotemporal analysis of Salmonella bacteraemia in Queensland, 2010–2019

Internal Medicine Journal, EarlyView.
Abstract Background Salmonellosis contributes to a significant burden on global healthcare systems. The impact of this foodborne bacterium is more pronounced when the infection is invasive, leading to bacteraemia and sepsis. Studies on invasive salmonellosis are few, and there is an urgent need to understand the spatial distribution of bacteraemia and ...
Naveen Manchal, Megan K Young, Maria Eugenia Castellanos, Oyelola A. Adegboye   +3 more
wiley   +1 more source

Design and Immunogenicity of a Nanoparticle Combination Vaccine for Salmonella in Poultry

Plant Biotechnology Journal, EarlyView.
ABSTRACT Salmonella enterica serovars (Salmonella) are common causes of bacterial gastroenteritis (salmonellosis) often associated with the consumption of poultry products. The control of Salmonella in broiler chickens is difficult because colonized birds may carry this pathogen undetected into the slaughterhouse and cause meat contamination.
Shabnam Shamriz, Angelo Kaldis, Carly A. Charron, Jordan T. VanderBurgt, Christopher P. Garnham, Moussa S. Diarra, Rima Menassa   +6 more
wiley   +1 more source

Assessment of the efficacy of large volume delayed sampling primary culture and pathogen reduction in preventing septic reactions from platelet transfusions

Transfusion, EarlyView.
Abstract Background Many mitigation processes have been introduced to reduce septic transfusion reactions (STRs) caused by the transfusion of bacterially contaminated PLTs. Methods The efficacy of primary culture and pathogen reduction is assessed in this review using data from long‐term hemovigilance programs in the US, Canada, UK, France, Switzerland,
Michael R. Jacobs
wiley   +1 more source