Results 91 to 100 of about 84,845 (267)

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, EarlyView.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

Control of Salmonella infections in animals and prevention of human foodborne Salmonella infections. WHO Consultation.

Bulletin of the World Health Organization, 1995
In many countries the incidence of human salmonella infections has markedly increased in recent years. To discuss recent developments and current understanding on the control of salmonella infections in animals, WHO organized a Consultation on the Control of Salmonella Infections in Animals: Prevention of Foodborne Salmonella Infections in Humans, held
openaire   +1 more source

Increased Pediatric Head and Neck Abscesses Following the COVID‐19 Pandemic

The Laryngoscope, EarlyView.
This study evaluated the impact of the COVID‐19 pandemic on pediatric head and neck abscesses at two tertiary care centers. Overall head and neck abscess incidence increased more than threefold in the post‐pandemic period compared with the pre‐pandemic period, with increases observed across all major abscess subtypes.
Marco DiBlasi, Ryan C. Higgins, Nicole Welch, Dwight Jones, Arthur J. Chang   +4 more
wiley   +1 more source

Evaluation of electrolyzed water to control fungal trunk pathogens in grapevine nurseries

Pest Management Science, Volume 81, Issue 4, Page 1740-1751, April 2025.
Electrolyzed water treatments could have promising applications in the grapevine nursery process to prevent or reduce infections caused by fungal trunk pathogens on grapevine propagation material. Abstract BACKGROUND Grapevine producers demand solutions to control fungal trunk pathogens (FTPs) in nurseries.
Mónica Berbegal, Adolfo Blasco, Grégoire Gaume, Pedro Amorós, Antônia Fernandes, José V. Ros‐Lis, Josep Armengol   +6 more
wiley   +1 more source

Discriminating Between Living and Dead Bacteria With a Field‐Effect Transistor Based on Nano‐Channels

Small, EarlyView.
Bacterial viability is determined in a complex environment with a field‐effect biological transistor with a limit of detection of a single bacterium. Living, antibiotic‐treated, thermally denatured, and inhibited E. coli generate distinct electrical signatures, enabling label‐free single‐cell detection and providing new opportunities for rapid ...
Bar Chen, Vijay Garika, Shubham Babbar, Pooja Verma, Tom Cohen, Kfir Kattav, Fanny Akselrod, Aparnaa Shree Vijaikumar, Shankar Bhattarai, Sherina Harilal, Evgeny Pikhay, Inna Shechter, Doron Greental, Muhammad Y. Bashouti, Izhar Ron, Yakov Roizin, Barak Akabayov, Gil Shalev   +17 more
wiley   +1 more source