Nanopore analysis of salvianolic acids in herbal medicines
Natural herbs, which contain pharmacologically active compounds, have been used historically as medicines. Conventionally, the analysis of chemical components in herbal medicines requires time-consuming sample separation and state-of-the-art analytical ...
Pingping Fan +6 more
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Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection [PDF]
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat cardiovascular diseases for hundreds of years.
Ho Jennifer, Hong Chuang-Ye
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Salvianolic acid B: a promising cardioprotective agent. [PDF]
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD). Its key bioactive compound, salvianolic acid B (SalB), has emerged as a promising therapeutic agent for CVD.
Shao Y, Zhai L, Jiang S, Sun F, Liu X.
europepmc +2 more sources
Cardiovascular Effects of Salvianolic Acid B [PDF]
Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
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Possible applications of salvianolic acid B against different cancers [PDF]
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing sustainable therapeutic regimens.
Iram Shahzadi +5 more
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Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds. [PDF]
Previously, we only apply a traditional Chinese medicine (TCM) Danshen-Chuanxiong-Honghua (DCH) for cardioprotection via anti-inflammation in rats of acute myocardial infarction by occluding coronary artery. Presently, we select not only DCH but also its
Fushun Wang +9 more
core +7 more sources
Salvianolic acid B is extracted from the roots and rhizomes of Danshen (Salvia miltiorrhiza Bge., family Labiatae). It is a water-soluble, weakly acidic drug that has demonstrated antitumor and anti-inflammatory effects on various organs and tissues such
Guannan He +6 more
doaj +1 more source
Salvianolic acid B alleviates cartilage tissue damage in rat models with osteoarthritis [PDF]
Objective To explore whether salvianolic acid B affects cartilage tissue damage, hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) in osteoarthritis rats. Methods A rat model of osteoarthritis was constructed, and rats were
QIAN Ligang, SUN Bo, YU Bo, CHEN Kang, MA Zheng, CHEN Taoping, WANG Yunfei
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Rosmarinic Acid Synthase 1 Phosphorylation by SmMAPK3 Is Required for Salicylic Acid-Induced Salvianolic Acid Accumulation in Salvia miltiorrhiza Hairy Roots. [PDF]
ABSTRACT Salvianolic acid is the main active component of Salvia miltiorrhiza and holds significant value in the clinical treatment of myocardial ischemia and hypoxia. Previous studies have shown that salicylic acid (SA) can significantly promote the accumulation of salvianolic acid, but its molecular mechanism remains incompletely understood.
Yin X +6 more
europepmc +2 more sources
Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage [PDF]
Salvianolic acid B (Sal B) is one of the main active ingredients of Salvia miltiorrhiza, with strong antioxidant effects. Recent findings have shown that Sal B has anti-inflammatory, anti-apoptotic, anti-fibrotic effects and can promote stem cell proliferation and differentiation, and has a beneficial effect on cardiovascular and cerebrovascular ...
Zhun Xiao +15 more
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