Results 41 to 50 of about 5,932,890 (256)

Role of High-Mobility Group Box-1 in Liver Pathogenesis [PDF]

open access: yes, 2019
High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location.
Huda, Nazmul   +3 more
core   +1 more source

Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis

open access: yesJournal of Inflammation, 2012
The aim of this study was to investigate the hepatoprotective effect of Matrine salvianolic acid B salt on carbon tetrachloride (CCl4)-induced hepatic fibrosis in rats. Salvianolic acid B and Matrine has long been used to treat liver fibrosis.
Gao Hong-Ying   +5 more
doaj   +1 more source

Phenolic profiles of cultivated, in vitro cultured and commercial samples of Melissa officinalis L. infusions [PDF]

open access: yes, 2013
Melissa officinalis L. (lemon balm) is normally consumed as infusions and presents therapeutic properties such as sedative, carminative and antispasmodic, being also included in some pharmaceutical preparations. The phenolic profiles of different samples
Barros, Lillian   +5 more
core   +1 more source

Salvianolic acid B promotes angiogenesis and inhibits cardiomyocyte apoptosis by regulating autophagy in myocardial ischemia

open access: yesChinese Medicine, 2023
Background Myocardial ischemia (MI) can cause angina, myocardial infarction, and even death. Angiogenesis is beneficial for ensuring oxygen and blood supply to ischemic tissue, promoting tissue repair, and reducing cell damage.
Qi Chen   +7 more
semanticscholar   +1 more source

Molecular Basis Underlying Hepatobiliary and Renal Excretion of Phenolic Acids of Salvia miltiorrhiza Roots (Danshen)

open access: yesFrontiers in Pharmacology, 2022
Phenolic acids are cardiovascular constituents (originating from the Chinese medicinal herb Salvia miltiorrhiza root/Danshen) of DanHong and many other Danshen-containing injections.
Jun-Lan Lu   +23 more
doaj   +1 more source

Overview on mentha and thymus polyphenols [PDF]

open access: yes, 2013
Mentha and Thymus are important genera of the Lamiaceae family widely distributed in the entire World and commonly used in traditional medicine. Indeed, many species of the two genera have been credited with a large list of health-benefit effects ...
Cardoso, Susana M., Pereira, Olívia R.
core   +1 more source

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro [PDF]

open access: yesMolecules, 2015
Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important active compounds of Salvia miltiorrhiza Bunge, on areca nut extract (ANE)-induced oral submucous ...
Jian-Ping Dai   +7 more
openaire   +3 more sources

Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

open access: yesAnnals of Hepatology, 2021
Introduction and objectives: The activation of hepatic stellate cells (HSCs) is the main cause of liver fibrosis. The beneficial effects of fibroblast growth factor (FGF) 19 on liver fibrosis were recently reported. The S.
Shuxia Tian   +5 more
doaj   +1 more source

Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

open access: yes, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu   +3 more
core   +1 more source

Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Salvianolic acid A (SAA) is a traditional Chinese medicine that has a good therapeutic effect on cardiovascular disease. However, the underlying mechanisms by which SAA improves mitochondrial respiration and cardiac function in diabetic cardiomyopathy ...
Difei Gong   +11 more
semanticscholar   +1 more source

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