Results 61 to 70 of about 5,932,890 (256)
Adapting tissue-engineered in vitro CNS models for high-throughput study of neurodegeneration [PDF]
, 2017 Neurodegenerative conditions remain difficult to treat, with the continuing failure to see therapeutic research successfully advance to clinical trials. One of the obstacles that must be overcome is to develop enhanced models of disease.
Cameron, GW +5 more
core +3 more sources
Frontiers in Pharmacology, 2022 Breast cancer is one of the most deadly malignancies in women worldwide. Salvia miltiorrhiza, a perennial plant that belongs to the genus Salvia, has long been used in the management of cardiovascular and cerebrovascular diseases.
Huan Zhao +9 more
doaj +1 more source
EETs mediate cardioprotection of salvianolic acids through MAPK signaling pathway
Acta Pharmaceutica Sinica B, 2013 Salvianolic acids, including salvianolic acid A (SAA) and salvianolic acid B (SAB), are the main water-soluble bioactive compounds isolated from the Chinese medicinal herb Danshen and have been shown to exert in vitro and in vivo cardiovascular ...
Shoubao Wang +8 more
doaj +1 more source
Preclinical and clinical examinations of
, 2006 Salvia miltiorrhiza (Labiatae, Laminaceae), danshen, is an annual sage mainly found in China and neighboring countries. The crude drug (dried root) and its preparations are currently used in China to treat patients suffering from heart attack, angina ...
Lien Eric +3 more
core +1 more source
Basil as functional and preserving ingredient in "serra da Estrela" cheese [PDF]
, 2016 All rights reserved. Antitumor, antimicrobial and antioxidant activities of basil were studied, along with its characterization in phenolic compounds, organic acids and soluble sugars.
Barreira, João C.M. +8 more
core +1 more source
Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury [PDF]
International Journal of Molecular Sciences, 2016 This study investigated the neuroprotective effect of salvianolic acids (SA) against ischemia/reperfusion (I/R) injury, and explored whether the neuroprotection was dependent on mitochondrial connexin43 (mtCx43) via the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathway.
Shuai Hou +5 more
openaire +2 more sources
PLoS ONE, 2015 Salvianolic acid B and rosmarinic acid are two main water-soluble active ingredients from Salvia miltiorrhiza with important pharmacological activities and clinical applications. The interactions between salvianolic acid B (or rosmarinic acid) and bovine
Xin Peng +4 more
doaj +1 more source
Salvianolic acid B inhibits autophagy and protects starving cardiac myocytes [PDF]
Acta Pharmacologica Sinica, 2010 To investigate the protective or lethal role of autophagy and the effects of Salvianolic acid B (Sal B) on autophagy in starving myocytes.Cardiac myocytes were incubated under starvation conditions (GD) for 0, 1, 2, 3, and 6 h. Autophagic flux in starving cells was measured via chloroquine (3 μmol/L).
Han, Xiao +2 more
openaire +3 more sources
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieIn patients with diabetic wounds, wound healing is impaired due to the presence of persistent oxidative stress, an altered inflammatory response, and impaired angiogenesis and epithelization.
Qin Lihao +7 more
semanticscholar +1 more source