Results 51 to 60 of about 5,932,890 (256)

Effects of gamma irradiation on cytotoxicity and phenolic compounds of Thymus vulgaris L. and Mentha x piperita L. [PDF]

, 2016
The aim of the present study was to evaluate the effects of gamma irradiation on cytotoxicity and phenolic compounds of Thymus vulgaris L. and Menta × piperita L. (methanolic extracts), used in traditional medicine.
Antonio, Amilcar L., Barros, Lillian, Cabo Verde, Sandra, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., Pereira, Eliana, Pimenta, Andreia I., Santos-Buelga, Celestino   +7 more
core   +1 more source

Salvianolic acid F suppresses KRAS-dependent lung cancer cell growth through the PI3K/AKT signaling pathway.

Phytomedicine, 2023
BACKGROUND KRAS mutation is a common driver of NSCLC, and there is a high proportion of lung cancer patients with KRAS G12C and G12D mutation. KRAS was previously considered an "undruggable" target, but the first KRAS G12C mutation-targeted drug AMG510 ...
Xuenan Hou, Chishun Zhou, Zuhui Liang, Huawei Qiu, Zhuming zhou, Huanjin Zheng, Zeyun Li, Ying Wang, Xiaoxiao Qi, Linlin Lu, Yang Cao, Jin Zheng   +11 more
semanticscholar   +1 more source

Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines [PDF]

, 2014
postprin
Chen, C, Fan, Y, Li, P, Qi, LW, So, KF, Yan, CP   +5 more
core   +1 more source

Salvianolic acid B ameliorates myocardial fibrosis in diabetic cardiomyopathy by deubiquitinating Smad7

Chinese Medicine, 2023
Background Salvianolic acid B (Sal B), a water-soluble phenolic compound derived from Salvia miltiorrhiza Bunge, is commonly used in Traditional Chinese Medicine to treat cardiovascular disease.
Hong Luo, Lingyun Fu, Xue-ting Wang, Yi-ni Xu, Ling Tao, Xiangchun Shen   +5 more
semanticscholar   +1 more source

Analysis on the Stability of Total Phenolic Acids and Salvianolic Acid B from by HPLC and HPLC-MS

Natural Product Communications, 2008
The stability of salvianolic acid B and total phenolic acids from Salvia miltiorrhiza in water solutions at different temperatures, in buffered aqueous solutions at different pHs and in biological fluids, including simulated gastric and intestinal fluids,
Man Xu, Jian Han, Hui-feng Li, Li Fan, Ai-hua Liu, De-an Guo   +5 more
doaj   +1 more source

Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization [PDF]

, 2015
Lemon balm (Melissa officinalis L.) is a member of the Lamiaceae family with a long story of human consumption. It has been consumed for decades, directly in food and as a decoction or an infusion for its medicinal purposes.
Barros, Lillian, Calhelha, Ricardo C., Carocho, Márcio, Ferreira, Isabel C.F.R., Morales, Patricia, Santos-Buelga, Celestino, Soković, Marina, Ćirić, Ana   +7 more
core   +1 more source

Neuroprotective mechanism of salvianolic acid B against cerebral ischemia–reperfusion injury in mice through downregulation of TLR4, p‐p38MAPK, p‐JNK, NF‐κB, and IL‐1β

Immunity, Inflammation and Disease, 2023
Tissue injury and inflammation are two potential outcomes of cerebral ischemia–reperfusion (I/R) injury. Salvianolic acid B (Sal B), isolated from the roots of Salvia miltiorrhiza, is one of the major water‐soluble compounds with a wide range of ...
Xiu-Fen Zheng, Xiang-jian Zhang, Lipeng Dong, Jing-Ru Zhao, Cong Zhang, Rong Chen   +5 more
semanticscholar   +1 more source

Salvianolic acid B in fibrosis treatment: a comprehensive review. [PDF]

Front Pharmacol
Fibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system due to its high incidence, disability, and mortality.
Liang Q, Liu X, Peng X, Luo T, Su Y, Xu X, Xie H, Gao H, Chen Z, Xie C.   +9 more
europepmc   +4 more sources

Dissection of the mechanism of traditional Chinese medical prescription-Yiqihuoxue formula as an effective anti-fibrotic treatment for systemic sclerosis [PDF]

, 2014
BACKGROUND: Systemic sclerosis (SSc) is a connective tissue fibrotic disease for which there is no effective treatment. Traditional Chinese Medicine (TCM), such as the Yiqihuoxue formula used in Shanghai TCM-integrated Hospital, has shown the efficacy of
Dongdong Chen, Haiyan Chu, Hejian Zou, Jin Yuan, Jiucun Wang, Li Jin, Ling Yu, Mengmeng Song, Qingmei Liu, Ting Wu, Wenyu Wu, Wenzhen Tu, Xiaodong Zhou, Yanyun Ma   +13 more
core   +2 more sources

Inhibition of chemically and mechanically activated Piezo1 channels as a mechanism for ameliorating atherosclerosis with salvianolic acid B

British Journal of Pharmacology, 2022
Salvianolic acid B (SalB) is effective for treating cardiovascular diseases. However, the molecular mechanisms underlying its therapeutic effects remain unclear.
Xianmei Pan, Rentao Wan, Yuman Wang, Silin Liu, Yu He, Bo Deng, Shangfei Luo, Yuan Chen, Lizhen Wen, Tianying Hong, Han Xu, Yifei Bian, Mingfeng Xia, Jing Li   +13 more
semanticscholar   +1 more source