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The asymmetric total synthesis of (+)-salvianolic acid A

Tetrahedron, 2016
Abstract An asymmetric synthesis of (+)-salvianolic acid A with cardioprotective properties, has been accomplished in a convergent manner in eight steps and 10.6% overall yield. This synthesis features an asymmetric addition of organometallics to optically pure 2,3-epoxypropionate in the presence of BF3·Et2O, Ru(III)-catalyzed directed C H ...
Yong Zheng, Wei-Bin Song, Li-Jiang Xuan
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Salvianolic acid J, a depside from Salvia flava

Phytochemistry, 1994
Abstract A new depside, salvianolic acid J, was isolated from an aqueous extract of Salvia flava as a trace component, together with salvianolic acids A and B. The major component was rosmarinic acid.
Chun-Bo Ai   +3 more
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Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury

Journal of Ethnopharmacology, 2012
Salvia miltiorrhiza and Panax notoginseng are popularly used traditional Chinese medicine for cardiovascular disorders and they are often used in the form of combination. However, mechanisms of their cardioprotective effects were still not clear.
Qing-Xi, Yue   +8 more
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[Study on preparation of salvianolic acid phospholipid compound].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014
To prepare salvianolic acid phospholipid compound. With the compound of salvianolic acids and soybean phospholipid as the index, mono-factor experiment and orthogonal design experiment were conducted to screen its technical parameters. According to the results, the optimal preparation conditions of salvianolic acid phospholipid compound were that THF ...
Xiao-Yun, Chen   +5 more
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[Research progress of salvianolic acid A].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation.
Li, Zhang   +12 more
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Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses

Neuroscience Letters, 2016
Experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), is a Th1 and Th17 cell-mediated CNS autoimmune disease. Therefore, immune regulation is a key target for therapy. Salvianolic acid B (Sal B) is a major water-soluble bioactive component of the famous traditional Chinese medicine Salvia miltiorrhiza, which is ...
Zhihui, Dong   +4 more
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[Study on application of salvianolic acids reference extract in quality control of Salvia miltiorrhiza and salvianolic acids for injection].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
The purpose of this study was to investigate the feasibility of the salvianolic acids reference extract for quality control for Salvia miltiorrhiza and salvianolic acids for injection. An Agilent ZORBAX SB-C18( 4. 6 mm×250 mm,5 μm) column was used with mobile phase consisting of 0. 1% formic acid-water and 0.
Yao-Lei, Li   +5 more
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Salvianolic Acid I: A New Depside fromSalvia cavaleriei

Planta Medica, 1994
A new depside named salvianolic acid I was isolated from the aqueous extract of SALVIA CAVALERIEI, along with salvianolic acids A, B, C, H, isosalvianolic acid C, lithospermic acid, and rosmarinic acid. The chemical struktures were determined by spectral analysis.
H J, Zhang, L N, Li
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ChemInform Abstract: The Total Synthesis of Salvianolic Acid F.

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vincent Dalla, Philippe Cotelle
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Salvianolic acid A inhibits tumor-associated angiogenesis by blocking GRP78 secretion

Naunyn-Schmiedeberg's Archives of Pharmacology, 2018
Glucose-regulated protein 78 (GRP78) often highly expresses in a wide range of tumors, which plays promotive functions due to its diversity of location in the development of tumor. Particularly, GRP78 can be secreted into microenvironment by tumor cells through the pathway of exosome, which promotes proliferation, angiogenesis, and drug resistance in ...
Yufei, Yang   +5 more
openaire   +2 more sources

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