Results 1 to 10 of about 929,762 (263)

Salvianolic acid B: a promising cardioprotective agent [PDF]

Frontiers in Immunology
Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma] is a core herb in traditional Chinese medicine widely used for treating cardiovascular diseases (CVD).
Yingchun Shao, Li Zhai, Shan Jiang, Fusheng Sun, Xuedong Liu   +4 more
doaj   +3 more sources

Salvianolic acid A inhibits ferroptosis and protects against intracerebral hemorrhage. [PDF]

Sci Rep
Intracerebral hemorrhage (ICH) is a common cerebral vascular disease with high incidence, disability, and mortality. Ferroptosis is a regulated type of iron-dependent, non-apoptotic programmed cell death. There is increasing evidence that ferroptosis may
Shi Y, Yan D, Nan C, Sun Z, Zhuo Y, Huo H, Jin Q, Yan H, Zhao Z.   +8 more
europepmc   +5 more sources

Computational and experimental studies of salvianolic acid A targets 3C protease to inhibit enterovirus 71 infection

Frontiers in Pharmacology, 2023
Hand, foot, and mouth disease (HFMD) is a common childhood infectious disease caused by enterovirus (EV) infection. EV71 is one of the major pathogens causing hand, foot, and mouth disease and is more likely to cause exacerbation and death than other ...
Sai Shi, Lei Xie, Sen Ma, Binghong Xu, Hailong An, Sheng Ye, Yaxin Wang   +6 more
doaj   +2 more sources

Repurposing SARS CoV 2 ligands identifies salvianolic acid C as potential antiviral candidate against human metapneumovirus through computational study [PDF]

Scientific Reports
Human Metapneumovirus (HMPV) is a leading cause of respiratory tract infections worldwide, with no approved antiviral treatments or vaccines currently available.
Pallavi Mosale Shanthappa, Nidheesh Melethadathil, Shiva Prasad Kollur   +2 more
doaj   +2 more sources

Inhibition of TLR4/MAPKs Pathway Contributes to the Protection of Salvianolic Acid A Against Lipotoxicity-Induced Myocardial Damage in Cardiomyocytes and Obese Mice

Frontiers in Pharmacology, 2021
The occurrence of lipotoxicity during obesity-associated cardiomyopathy is detrimental to health. Salvianolic acid A (SAA), a natural polyphenol extract of Salvia miltiorrhiza Bunge (Danshen in China), is known to be cardioprotective.
Zhen Yang, Zhen Yang, Zhen Yang, Yanli Chen, Yanli Chen, Zhaoyuan Yan, Tian Tian Xu, Xiangyao Wu, Aiwen Pi, Qingsheng Liu, Hui Chai, Hui Chai, Songtao Li, Songtao Li, Xiaobing Dou, Xiaobing Dou   +15 more
doaj   +2 more sources

Recent Advances in Transcription Factor–Mediated Regulation of Salvianolic Acid Biosynthesis in Salvia miltiorrhiza [PDF]

Plants
Salvia miltiorrhiza Bunge is a traditional Chinese medicinal plant whose roots are rich in water-soluble phenolic acids. Rosmarinic acid and salvianolic acid B are representative components that confer antibacterial, antioxidant, and cardio ...
Song Chen, Fang Peng, Shan Tao, Xiufu Wan, Hailang Liao, Peiyuan Wang, Can Yuan, Changqing Mao, Xinyi Zhao, Chao Zhang, Bing He, Mingzhi Zhong   +11 more
doaj   +2 more sources

Gibberellin-Induced Transcription Factor SmMYB71 Negatively Regulates Salvianolic Acid Biosynthesis in Salvia miltiorrhiza [PDF]

Molecules
Salvia miltiorrhiza, the valuable traditional Chinese medicinal plant, has been used in clinics for thousands of years. The water-soluble salvianolic acid compounds are bioactive substances used in treating many diseases.
Cuicui Han, Xingwen Dong, Xiaowen Xing, Yun Wang, Xiaobing Feng, Wenjuan Sang, Yifei Feng, Luyao Yu, Mengxuan Chen, Hongyuan Hao, Taohong Huang, Bailin Li, Wenhui Wu, Zheng Zhou, Ying He   +14 more
doaj   +2 more sources

Ultrasonic-assisted nanofiltration separation recovering salvianolic acid B from ethanol wastewater [PDF]

Ultrasonics Sonochemistry
The transformation of salvianolic acid B brought on by heat treatment recovery of ethanol eluent, which is a difficult problem in pharmaceutical technology, affects the purity of raw material when the medicinal raw material salvianolic acid B is purified
Cunyu Li, Yun Ma, Yangyang Xu, Ranyun Qiu, Xin Shen, Lulu Huang, Anrong Liu, Mingming Li, Yunfeng Zheng, Xinglei Zhi   +9 more
doaj   +2 more sources

The combination of salvianolic acid A with latamoxef completely protects mice against lethal pneumonia caused by methicillin-resistant Staphylococcus aureus

Emerging Microbes and Infections, 2020
Staphylococcus aureus (S. aureus), especially methicillin-resistant Staphylococcus aureus (MRSA), is a major cause of pneumonia, resulting in severe morbidity and mortality in adults and children.
Dan Mu, Yongxin Luan, Lin Wang, Zeyuan Gao, Panpan Yang, Shisong Jing, Yanling Wang, Hua Xiang, Tiedong Wang, Dacheng Wang   +9 more
doaj   +2 more sources

Salvianolic acid A exerts antiviral effects by targeting the S protein, a virulence factor of porcine epidemic diarrhea virus [PDF]

Journal of Virology
Porcine epidemic diarrhea virus (PEDV), a member of the Coronaviridae family, infects the small intestinal epithelial cells of pigs, causing porcine epidemic diarrhea (PED), which is particularly severe in young piglets.
Zhaoran Zhang, Yan Zeng, Yaning Lv, Xiaodan Li, Jiaqi Liu, Ziyi Zhang, Ze Tong, Wenqi Dong, Di Liu, Chen Tan, Chenchen Wang   +10 more
doaj   +2 more sources