Results 11 to 20 of about 929,762 (263)

Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo [PDF]

Frontiers in Pharmacology, 2020
Osteoarthritis (OA) is a degenerative disease found in middle-aged and elderly people, which seriously affects their quality of life. The anti-inflammatory and anti-apoptosis pharmacological effects of salvianolic acid A (SAA) have been shown in many ...
Yifan Wu, Zhanghong Wang, Zeng Lin, Xin Fu, Jingdi Zhan, Kehe Yu   +5 more
doaj   +4 more sources

Effects of salvianolic acid A and salvianolic acid B in renal interstitial fibrosis via PDGF-C/PDGFR-α signaling pathway.

Phytomedicine, 2022
BACKGROUND Renal interstitial fibrosis (RIF) is the main pathological feature of end-stage renal disease (ESRD) caused by various chronic kidney diseases (CKD), and is closely related to renal dysfunction and patient prognosis. Salvianolic acid A (Sal A)
Lan Yao, Renjie Zhao, Shiyang He, Q. Feng, Y. Qiao, Peikang Wang, Jun Li   +6 more
semanticscholar   +3 more sources

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro [PDF]

Molecules, 2015
Salvia miltiorrhiza Bunge has been reported to possess excellent antifibrotic activity. In this study, we have investigated the effect and mechanism of tanshinone IIA (Tan-IIA), salvianolic acid A (Sal-A) and salvianolic acid B (Sal-B), the important ...
Jian-Ping Dai, Dan-Xia Zhu, Jiang-Tao Sheng, Xiao-Xuan Chen, Wei-Zhong Li, Ge-Fei Wang, Kang-Sheng Li, Yun Su   +7 more
doaj   +5 more sources

Alleviatory effects of Danshen, Salvianolic acid A and Salvianolic acid B on PC12 neuronal cells and Drosophila melanogaster model of Alzheimer’s disease [PDF]

Journal of Ethnopharmacology, 2020
Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder worldwide. Its pathogenesis involves the hallmark aggregation of amyloid-beta (Aβ).
F. Tan, A. Ting, N. Najimudin, N. Watanabe, G. Azzam   +4 more
semanticscholar   +3 more sources

Comparison of Salvianolic Acid A Adsorption by Phenylboronic-Acid-Functionalized Montmorillonites with Different Intercalators

Molecules, 2023
Due to its success in treating cardio-cerebrovascular illnesses, salvianolic acid A (SAA) from Salvia miltiorrhiza is of major importance for effective acquisition.
Jun Qian, Jiajia Su, Weihuan Zeng, Yue Wang, Yingyuan Hu, Guoyin Kai   +5 more
doaj   +3 more sources

Salvianolic Acid Modulates Physiological Responses and Stress-Related Genes That Affect Osmotic Stress Tolerance in Glycine max and Zea mays

Frontiers in Plant Science, 2022
Drought is a serious threat worldwide to soybean and maize production. This study was conducted to discern the impact of salvianolic acid treatment on osmotic-stressed soybean (Glycine max L.) and maize (Zea mays L.) seedlings from the perspective of ...
Elham Ahmed Kazerooni, Abdullah Mohammed Al-Sadi, Umer Rashid, Il-Doo Kim, Sang-Mo Kang, In-Jung Lee   +5 more
doaj   +1 more source

Inhibitory Effect of Salvia miltiorrhiza Extract and Its Active Components on Cervical Intraepithelial Neoplastic Cells

Molecules, 2022
The effective treatment of cervical intraepithelial neoplasia (CIN) can prevent cervical cancer. Salvia miltiorrhiza is a medicinal and health-promoting plant. To identify a potential treatment for CIN, the effect of S.
Xuejiao Leng, Hongfei Kan, Qinhang Wu, Cunyu Li, Yunfeng Zheng, Guoping Peng   +5 more
doaj   +1 more source

Salvianolic acid A alleviates heart failure with preserved ejection fraction via regulating TLR/Myd88/TRAF/NF-κB and p38MAPK/CREB signaling pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Heart failure with preserved ejection fraction (HFpEF) is a morbid, fatal, and common syndrome for which lack of evidence-based therapies. Salvianolic acid A (SAA), a major active ingredient of Salvia miltiorrhiza Burge, has shown potential to protect ...
Awaguli Dawuti, Shuchan Sun, Ranran Wang, Difei Gong, Ruiqi Liu, Dewen Kong, Tian‐yi Yuan, Jian Zhou, Yang Lu, Shoubao Wang, Guan-hua Du, Lianhua Fang   +11 more
semanticscholar   +1 more source

Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023
Salvianolic acid A (SAA) is a traditional Chinese medicine that has a good therapeutic effect on cardiovascular disease. However, the underlying mechanisms by which SAA improves mitochondrial respiration and cardiac function in diabetic cardiomyopathy ...
Difei Gong, Shuhao Sun, Ran-Ran Wang, Awaguli Dawuti, Dewen Kong, Ruizhi Liu, L. Du, Shou-bao Wang, Yang Lu, Tian‐yi Yuan, Guangsheng Du, L. Fang   +11 more
semanticscholar   +1 more source

Salvianolic Acid A Protects against Acetaminophen-Induced Hepatotoxicity via Regulation of the miR-485-3p/SIRT1 Pathway

Antioxidants, 2023
The vast majority of drug-induced liver injury is mainly attributed to acetaminophen (APAP) overdose. Salvianolic acid A (Sal A), a powerful water-soluble compound obtained from Salvia miltiorrhiza, has been confirmed to exert hepatoprotective effects ...
Fan Tang, Zhecheng Wang, Junjun Zhou, Jihong Yao   +3 more
semanticscholar   +1 more source