Results 31 to 40 of about 929,762 (263)

Salvianolic acid B in fibrosis treatment: a comprehensive review. [PDF]

Front Pharmacol
Fibrosis is a public health issue of great concern characterized by the excessive deposition of extracellular matrix, leading to the destruction of parenchymal tissue and organ dysfunction that places a heavy burden on the global healthcare system due to its high incidence, disability, and mortality.
Liang Q, Liu X, Peng X, Luo T, Su Y, Xu X, Xie H, Gao H, Chen Z, Xie C.   +9 more
europepmc   +4 more sources

The anti-tumor and renoprotection study of E-[c(RGDfK)2]/folic acid co-modified nanostructured lipid carrier loaded with doxorubicin hydrochloride/salvianolic acid A

Journal of Nanobiotechnology, 2022
Background Poor in vivo targeting of tumors by chemotherapeutic drugs reduces their anti-cancer efficacy in the clinic. The discovery of over-expressed components on the tumor cell surface and their specific ligands provide a basis for targeting tumor ...
Bing Zhang, Ying Zhang, Wenli Dang, Bin Xing, Chang-hai Yu, Pan Guo, Jiaxin Pi, Xiuping Deng, Dongli Qi, Zhidong Liu   +9 more
semanticscholar   +1 more source

Salvianolic Acid Y: A New Protector of PC12 Cells against Hydrogen Peroxide-Induced Injury from Salvia officinalis

Molecules, 2015
Salvianolic acid Y (TSL 1), a new phenolic acid with the same planar structure as salvianolic acid B, was isolated from Salvia officinalis. The structural elucidation and stereochemistry determination were achieved by spectroscopic and chemical methods ...
Jun Gong, Aichun Ju, Dazheng Zhou, Dekun Li, Wei Zhou, Wanli Geng, Bing Li, Li Li, Yanjie Liu, Ying He, Meizhen Song, Yunhua Wang, Zhengliang Ye, Ruichao Lin   +13 more
doaj   +1 more source

Tanshinone and salvianolic acid biosynthesis are regulated by SmMYB98 in Salvia miltiorrhiza hairy roots

Journal of Advanced Research, 2020
Salvia miltiorrhiza Bunge is an herb rich in bioactive tanshinone and salvianolic acid compounds. It is primarily used as an effective medicine for treating cardiovascular and cerebrovascular diseases.
Xiaolong Hao, Zhongqiang Pu, Gang Cao, Dawei You, Yang Zhou, Changping Deng, Min Shi, Shivraj Hariram Nile, Yao Wang, Wei Zhou, Guoyin Kai   +10 more
doaj   +1 more source

Salvianolic Acid B Prevents Arsenic Trioxide-Induced Cardiotoxicity In Vivo and Enhances Its Anticancer Activity In Vitro [PDF]

, 2013
Clinical attempts to reduce the cardiotoxicity of arsenic trioxide (ATO) without compromising its anticancer activities remain to be an unresolved issue.
Chen, Rongchang, Dong, Xi, Luo, Yun, Qin, Meng, Sun, Guibo, Sun, Hong, Sun, Xiaobo, Wang, Min, Wu, Ping, Yao, Fan, Zhang, Qiang   +10 more
core   +3 more sources

Salvianolic acid A from Danhong Injection induces vasorelaxation by Regulating L-type calcium channel in isolated mouse arteries.

Journal of Ethnopharmacology, 2022
ETHNOPHARMACOLOGICAL RELEVANCE Danhong injection (DHI), which is a Chinese clinical prescription consists of Radix et Rhizoma Salviae Miltiorrhizae (Salvia miltiorrhiza Bge., Labiatae, Danshen in Chinese) and Flos Carthami (Carthamus tinctorius L ...
Yi-Ke Lin, Yi-jun Chen, Jiesheng Li, Yuli Chen, Dong He, Rui Zuo, Min Xiao, Danping Xu, Chaoyang Zheng, Wei Wang, Rong-Rong He, Yang Chen   +11 more
semanticscholar   +1 more source

Salvianolic acid B attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction via Nrf2-Gpx4 pathway-mediated ferroptosis

Di-san junyi daxue xuebao, 2022
Objective To determine the improving effect of salvianolic acid B on renal interstitial fibrosis (RIF) of rats with unilateral ureteral obstruction (UUO) based on ferroptosis mediated by nuclear factor erythroid 2-related factor 2 (Nrf2)-glutathione ...
SUN Yuanbo, SONG Yanran, WANG Shiqi, SUN Lixin, LI Guiqin   +4 more
doaj   +1 more source

How gamma and electron-beam irradiations modulate phenolic profile expression in Melissa officinalis L. and Melittis melissophyllum L. [PDF]

, 2018
Owing to the overall increase in herbal infusions’ consumption, there's a progressively higher need of suitable plant material, as well as adequate conservation techniques to maintain its quality. Among, the available technologies, irradiation is gaining
Antonio, Amilcar L., Barreira, João C.M., Barros, Lillian, Ferreira, Isabel C.F.R., Pereira, Eliana, Santos-Buelga, Celestino   +5 more
core   +2 more sources

RGD-modified multifunctional nanoparticles encapsulating salvianolic acid A for targeted treatment of choroidal neovascularization

Journal of Nanobiotechnology, 2021
Background The development of alternative anti-angiogenesis therapy for choroidal neovascularization (CNV) remains a great challenge. Nanoparticle systems have emerged as a new form of drug delivery in ocular diseases.
Junxiu Zhang, Jingyi Zhu, Lingzhou Zhao, K. Mao, Qing Gu, Dongli Li, Jinhua Zhao, Xingwei Wu   +7 more
semanticscholar   +1 more source

Salvianolic acid B protects the myelin sheath around injured spinal cord axons

Neural Regeneration Research, 2016
Salvianolic acid B, an active pharmaceutical compound present in Salvia miltiorrhiza, exerts a neuroprotective effect in animal models of brain and spinal cord injury.
Zhe Zhu, Lu Ding, Wen-feng Qiu, Hong-fu Wu, Rui Li   +4 more
doaj   +1 more source