Results 181 to 190 of about 11,816 (210)

Antiplatelet and antithrombotic activities of salvianolic acid A

Thrombosis Research, 2010
Salvianolic acid A (SAA), the water-soluble phenolic acids in Salvia miltiorrhiza, has shown the most potent bioactivities, including protection against cerebral lesion, defense from oxidative damage and improvement of remembrance. In the present study, we studied the antiplatelet and antithrombotic effects of a newly synthesized SAA with different ...
Hua-Ying, Fan, Feng-Hua, Fu, Ming-Yan, Yang, Hui, Xu, Ai-Hong, Zhang, Ke, Liu   +5 more
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Bioavailability of salvianolic acid B and effect on blood viscosities after oral administration of salvianolic acids in beagle dogs

Archives of Pharmacal Research, 2009
Salvianolic acid B (SalB) is an active component isolated from Chinese herbal medicine Salvia miltiorrhiza. The aim of this study was to investigate the extent of absolute oral bioavailability (F) of SalB in beagle dogs and the effect on blood viscosity after intravenous and oral administration of Salvianolic acids (SAs). A gradient elution HPLC method
Dong-Yan, Gao, Li-Mei, Han, Li-Hong, Zhang, Xiao-Ling, Fang, Jian-Xin, Wang   +4 more
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The total synthesis of salvianolic acid F

Tetrahedron, 1999
Abstract An expeditious synthesis of salvianolic acid F 2 is described in 10% overall yield. Tetramethyl salvianolic acid F 3 was obtained in six steps in 39% overall yield and was converted into the target molecule using boron tribromide in 26% yield.
Vincent Dalla, Philippe Cotelle
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Research progress of salvianolic acid A

China Journal of Chinese Materia Medica, 2011
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation.
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Synthesis of (+)-salvianolic acid A from sodium Danshensu

Tetrahedron, 2018
Abstract (+)-Salvianolic acid A, one of the most active components in the traditional Chinese medicine Danshen, has been synthesized over 10 steps in 6.5% overall yield. Starting from inexpensive ortho-vanillin and sodium Danshensu (synthesized via asymmetric catalysis in our group), the process consists of the following: A Wittig reaction that gives
Kai Xu, Hao Liu, Delong Liu, Cheng Sheng, Jiefeng Shen, Wanbin Zhang   +5 more
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The asymmetric total synthesis of (+)-salvianolic acid A

Tetrahedron, 2016
Abstract An asymmetric synthesis of (+)-salvianolic acid A with cardioprotective properties, has been accomplished in a convergent manner in eight steps and 10.6% overall yield. This synthesis features an asymmetric addition of organometallics to optically pure 2,3-epoxypropionate in the presence of BF3·Et2O, Ru(III)-catalyzed directed C H ...
Yong Zheng, Wei-Bin Song, Li-Jiang Xuan
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Salvianolic acid J, a depside from Salvia flava

Phytochemistry, 1994
Abstract A new depside, salvianolic acid J, was isolated from an aqueous extract of Salvia flava as a trace component, together with salvianolic acids A and B. The major component was rosmarinic acid.
Chun-Bo Ai, Qiao-Hong Deng, Wan-Zhi Song, Lian-Niang Li   +3 more
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[Study on preparation of salvianolic acid phospholipid compound].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2014
To prepare salvianolic acid phospholipid compound. With the compound of salvianolic acids and soybean phospholipid as the index, mono-factor experiment and orthogonal design experiment were conducted to screen its technical parameters. According to the results, the optimal preparation conditions of salvianolic acid phospholipid compound were that THF ...
Xiao-Yun, Chen, Zhen-Hai, Zhang, Dan, Liu, Dan-Hong, Yu, E, Sun, Xiao-Bin, Jia   +5 more
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[Research progress of salvianolic acid A].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation.
Li, Zhang, Weiku, Zhang, Ying, Zhao, Xiuying, Yang, Lianhua, Fang, Shoubao, Wang, Lili, Shi, Xiaoyan, Yu, Subo, Wang, Haiguang, Yang, Jialin, Sun, Shuo, Tian, Guanhua, Du   +12 more
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Salvianolic acid B ameliorates CNS autoimmunity by suppressing Th1 responses

Neuroscience Letters, 2016
Experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), is a Th1 and Th17 cell-mediated CNS autoimmune disease. Therefore, immune regulation is a key target for therapy. Salvianolic acid B (Sal B) is a major water-soluble bioactive component of the famous traditional Chinese medicine Salvia miltiorrhiza, which is ...
Zhihui, Dong, Dihui, Ma, Ye, Gong, Tingmin, Yu, Gang, Yao   +4 more
openaire   +2 more sources