Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection [PDF]
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat cardiovascular diseases for hundreds of years.
Ho Jennifer, Hong Chuang-Ye
doaj +5 more sources
EETs mediate cardioprotection of salvianolic acids through MAPK signaling pathway
Salvianolic acids, including salvianolic acid A (SAA) and salvianolic acid B (SAB), are the main water-soluble bioactive compounds isolated from the Chinese medicinal herb Danshen and have been shown to exert in vitro and in vivo cardiovascular ...
Shoubao Wang +8 more
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Comparative metabolomic profiling and chemometric correlation of Salvia rosmarinus Spenn. and Origanum vulgare L. with antibacterial, antioxidant and anti-inflammatory activities [PDF]
The Lamiaceae plants are recognized in folk medicine for their antibacterial and anti-inflammatory properties. This study reports the first MS-based metabolomics analysis, integrating with chemometrics to explore metabolome heterogeneity in Salvia ...
Alaa Y. Zakarya +7 more
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Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats [PDF]
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Huang J +11 more
europepmc +2 more sources
Recent Advances in Transcription Factor–Mediated Regulation of Salvianolic Acid Biosynthesis in Salvia miltiorrhiza [PDF]
Salvia miltiorrhiza Bunge is a traditional Chinese medicinal plant whose roots are rich in water-soluble phenolic acids. Rosmarinic acid and salvianolic acid B are representative components that confer antibacterial, antioxidant, and cardio ...
Song Chen +11 more
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Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H2O2-induced injury in PC12 cells [PDF]
Purpose The objective of this investigation was to produce fermented solid-state products of Salvia miltiorrhiza Bunge (SMB) utilizing Shiraia bambusicola Henn. (FSSMB).
Qiaona Wang +7 more
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Cardiovascular Effects of Salvianolic Acid B [PDF]
Salvianolic acid B (SAB, Sal B) is the representative component of phenolic acids derived from the dried root and rhizome ofSalvia miltiorrhizaBge (Labiatae) which has been used widely and successfully in Asian countries for clinical therapy of various vascular disturbance-related diseases for hundreds of years.
Wang, Jie, Xiong, Xingjiang, Feng, Bo
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Salvianolic Acids Alleviate Chronic Mild Stress-Induced Depressive-Like Behaviors in Rats
Background: Salvianolic acids possess anti-inflammatory properties. This study investigated the therapeutic effect of salvianolic acids on chronic mild stress (CMS)-induced depressive-like behaviors in rats and the involvement of toll-like receptor 4 ...
Fengya Zhen +6 more
doaj +1 more source
Phenolic acids are cardiovascular constituents (originating from the Chinese medicinal herb Salvia miltiorrhiza root/Danshen) of DanHong and many other Danshen-containing injections.
Jun-Lan Lu +23 more
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Possible applications of salvianolic acid B against different cancers [PDF]
Cancer is the second death causing disease worldwide after cardiovascular abnormalities. The difficulty in treating tumor cells with more precise targeted interventions and recurrence of cancer after treatment may pose great difficulty in developing sustainable therapeutic regimens.
Iram Shahzadi +5 more
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