Results 61 to 70 of about 11,816 (210)

Integrative Omics Analyses Reveal the Effects of Copper Ions on Salvianolic Acid Biosynthesis

Frontiers in Plant Science, 2021
Salvianolic acids, a group of secondary metabolites produced by Salvia miltiorrhiza, are widely used for treating cerebrovascular diseases. Copper is recognized as a necessary microelement and plays an essential role in plant growth.
Yaping Xiang, Xiaoxiao Wang, Wei Song, Jinfa Du, Xiaojian Yin   +4 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

The Effect of Salvianolic Acid on Vascular Protection and Possible Mechanisms [PDF]

Oxidative Medicine and Cellular Longevity, 2020
Salvia miltiorrhiza (Danshen), as an important traditional Chinese medicinal plant, has been used in China for the treatment of cardiovascular diseases for hundreds of years. Salvianolic acids (salvianolic acid A and salvianolic acid B) as the most abundant water-soluble component extracted from Salvia miltiorrhiza have attracted more and more ...
Yalan Wu, Suowen Xu, Xiao Yu Tian
openaire   +2 more sources

Cloning and characterization of a putative R2R3 MYB transcriptional repressor of the rosmarinic acid biosynthetic pathway from Salvia miltiorrhiza.

PLoS ONE, 2013
Salvia miltiorrhiza Bunge is one of the most renowned traditional medicinal plants in China. Phenolic acids that are derived from the rosmarinic acid pathway, such as rosmarinic acid and salvianolic acid B, are important bioactive components in S ...
Shuncang Zhang, Pengda Ma, Dongfeng Yang, Wenjing Li, Zongsuo Liang, Yan Liu, Fenghua Liu   +6 more
doaj   +1 more source

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, Volume 13, Issue 26, 8 May 2026.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source

Rosmarinic Acid Derivatives’ Inhibition of Glycogen Synthase Kinase-3β Is the Pharmacological Basis of Kangen-Karyu in Alzheimer’s Disease

Molecules, 2018
Inhibition of glycogen synthase kinase 3β (GSK-3β) is considered to be the central therapeutic approach against Alzheimer’s disease (AD).
Pradeep Paudel, Su Hui Seong, Yajuan Zhou, Chan Hum Park, Takako Yokozawa, Hyun Ah Jung, Jae Sue Choi   +6 more
doaj   +1 more source

Phytochemicals and bioactive properties of Ilex paraguariensis: an in-vitro comparative study between the whole plant, leaves and stems [PDF]

, 2015
Leaves, stems and whole plant of Ilex paraguariensis (yerba mate) were characterized in terms of their chemical composition and biological activities in order to determine which part of the plant is more interesting to develop bioactive formulations. The
Barros, Lillian, Bracht, Adelar, Calhelha, Ricardo C., Corrêa, Rúbia C.G., Ferreira, Isabel C.F.R., Matsushita, Makoto, Peralta, Rosane M., Santos-Buelga, Celestino, Souza, Aloisio Henrique Pereira de   +8 more
core   +1 more source

Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Salvia miltiorrhiza (Danshen) contains bioactive tanshinones, including tanshinone IIA, cryptotanshinone, and tanshinone I, that exert cardioprotective effects through coordinated modulation of vascular endothelial growth factor receptor (VEGFR), transforming growth factor beta 1 (TGF‐β1), transforming growth factor beta receptor (TGF‐βR), toll‐like ...
Akash Vikal, Rashmi Maurya, Preeti Patel, Balak Das Kurmi, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Salvianolic acid B stimulates osteogenesis in dexamethasone-treated zebrafish larvae [PDF]

Acta Pharmacologica Sinica, 2016
Our previous studies show that salvianolic acid B (Sal B) promotes osteoblast differentiation and matrix mineralization. In this study, we evaluated the protective effects of Sal B on the osteogenesis in dexamethasone (Dex)-treated larval zebrafish, and elucidated the underlying mechanisms.At 3 d post fertilization, wild-type AB zebrafish larvae or ...
Shi-Ying, Luo, Jing-Feng, Chen, Zhi-Guo, Zhong, Xiao-Hua, Lv, Ya-Jun, Yang, Jing-Jing, Zhang, Liao, Cui   +6 more
openaire   +2 more sources

Salvia verticillata (L.)—Biological Activity, Chemical Profile, and Future Perspectives

Pharmaceuticals
Species belonging to the genus Salvia, Lamiaceae, have been deeply involved in the folk medicine of different nations since ancient times. Lilac sage, or Salvia verticillata L. (S. verticillata) is a less studied species from the genus. However, it seems
Stanislava Ivanova, Zoya Dzhakova, Radiana Staynova, Kalin Ivanov   +3 more
doaj   +1 more source