Results 71 to 80 of about 828,082 (149)

Antioxidant Chemistry of Phenolics in Chinese Herbal Medicines: A Holism‐Based Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Phenolic antioxidants in CHMs mainly include chalcone, stilbene, flavonoid, xanthone, and Diels–Alder‐type adducts. They undergo direct and indirect pathways to exert antioxidant action. The indirect pathway is transition metal‐chelating, while the direct pathway comprises several redox‐based reactions (e.g., SET and HAT) and RAF reactions.
Xican Li
wiley   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

iMetaMed, Volume 2, Issue 3, September 2026.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo, Yang Zhang, Xin Wang, Shan Cao, Jun Xu   +4 more
wiley   +1 more source

Salvianolic acid B inhibits mitochondrial dysfunction by up-regulating mortalin

, 2017
Salvianolic acid B is an antioxidative ingredient derived from Radix Salviae miltiorrhizae that has been widely used to treat liver diseases. However, the therapeutic mechanism underlying Salvianolic acid B has remained largely unknown.
Ling Yang, Yingying Hu, Yunxia Liu, Ji Zuo, Wen Liu, Qiukai E   +5 more
core   +1 more source

Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay

, 2015
Traditional Chinese medicines (TCMs) have been used in the clinic for thousands of years. Their reliable therapeutic efficacies are closely related to their multi-target mechanisms of action (MOAs).
Sun, Guangwei, Wei, Lai, Wang, Jixia, Shi, Liying, Liang, Xinmiao, He, Jian, Zhang, Xiuli, Hou, Tao, Zhou, Nan   +8 more
core   +1 more source

Neuroprotective Effects of Geopung-Chunghyuldan Based on Its Salvianolic Acid B Content Using an In Vivo Stroke Model

, 2023
Background: Geopung-Chunghyuldan (GCD) has neuroprotective properties. Salviae miltiorrhizae Radix plays an essential role in GCD’s effect. The Salviae miltiorrhizae Radix marker compound is salvianolic acid B; however, its content is not uniform among ...
Sang-Kwan Moon, Jung-Mi Park, Chang-Nam Ko, Seong-Uk Park, Seungwon Kwon, Ki-Ho Cho, Seung-Yeon Cho, Woo-Sang Jung, Han-Gyul Lee   +8 more
core   +1 more source

Salvianolic acid-A induces apoptosis, mitochondrial membrane potential loss and DNA damage in small cell lung cancer cell lines [PDF]

, 2015
Purpose: To examine the anticancer effect of salvianolic acid-A against human small cell lung cancer (SCLC) cells (H-69).Methods: In vitro antiproliferative effect of salvianolic acid against SCLC cell lines was evaluated by 3-(4,5-dimethylthiazol-2-yl ...
Guan, Y, Li, X-M, Li, J, Wang, L-Q, Wang, D-F   +4 more
core   +1 more source

Inhibition Effects of Salvianolic Acid M and Rosmarinic Acid in Salvia deserta Schang on Human Aldose Reductase [PDF]

, 2020
[Objectives] This study aimed to investigate the inhibition effects of two chemical constituents in Salvia deserta Schang on human aldose reductase (AR).
WU, Jie, WANG, Xinling, HE, Qian, YANG, Jian   +3 more
core   +1 more source

Comparative metabolomic profiling and chemometric correlation of Salvia rosmarinus Spenn. and Origanum vulgare L. with antibacterial, antioxidant and anti-inflammatory activities

Scientific Reports
The Lamiaceae plants are recognized in folk medicine for their antibacterial and anti-inflammatory properties. This study reports the first MS-based metabolomics analysis, integrating with chemometrics to explore metabolome heterogeneity in Salvia ...
Alaa Y. Zakarya, Dalia M. Rasheed, Ayat M. Emad, Mohamed A. Farag, Zeinab M. Goda, Omnia Karem M. Riad, Sally T. K. Tohamy, Ahmed H. Elbanna   +7 more
doaj   +1 more source

Salvianolic Acid B Inhibits Low-Density Lipoprotein Oxidation and Neointimal Hyperplasia in Endothelium-Denuded Hypercholesterolaemic Rabbits

, 2012
BACKGROUND: Atherosclerosis and restenosis are inflammatory responses involving free radicals and lipid peroxidation and may be prevented/cured by antioxidant-mediated lipid peroxidation inhibition.
林豐彥;陳永祥;裘正健;蕭明熙;蔡建松;林幸榮;陳玉怜, LIN, FENG-YEN;CHEN, YUNG-HSIANG;CHIU, JENG-JIANN;SHIAO, MING-SHI;TSAI, CHIEN-SUNG;LIN, SHING-JONG;CHEN, YUH-LIEN   +1 more
core   +1 more source

Genome-Wide Identification and Characterization of the Salvia miltiorrhiza Histone Deacetylase (HDAC) Family in Response to Multiple Abiotic Stresses

Plants
Salvia miltiorrhiza is a plant commonly used in traditional Chinese medicine. Its material bases for treating diseases are tanshinones and phenolic acids, including salvianolic acids.
Junyu Chen, Yuxin Ying, Lingtiao Yao, Zhangting Xu, Zhenming Yu, Guoyin Kai   +5 more
doaj   +1 more source