Results 101 to 110 of about 947,067 (264)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Convergence analysis of sample average approximation for a class of stochastic nonlinear complementarity problems: from two-stage to multistage. [PDF]
Numer Algorithms, 2022 Jiang J, Sun H, Zhou B.
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A New Gap Function for Vector Variational Inequalities with an Application
Journal of Applied Mathematics, 2013 We consider a vector variational inequality in a finite-dimensional space. A new gap function is proposed, and an equivalent optimization problem for the vector variational inequality is also provided.
Hui-qiang Ma +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
DronesThis paper addresses the cooperative task assignment problem for heterogeneous unmanned aerial vehicles with time windows considering uncertain fuel consumption. In the scenario where probabilistic fuel consumption exists and its distribution needs to be
Zhichao Gao +4 more
doaj +1 more source
Analysis of the Accuracy of Uncertainty Noise Measurement
Archives of Acoustics, 2015 The paper formulates some objections to the results of the evaluation of uncertainty in noise measurement which are presented in two standards: PN-ISO 9612 (2004) and DIN 45 641 (1990).
Bartosz PRZYSUCHA +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Statistical approximation of multicriteria problems of stochastic programming
Доповiдi Нацiональної академiї наук УкраїниThe article validates an approximation technique for solving multiobjective stochastic optimization problems. As a generalized model of a stochastic system to be optimized, a vector "input–random output" system is considered.
B.V. Norkin
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source