Results 161 to 170 of about 32,954,715 (297)

Predicting the alternative conformation of a known protein structure based on the distogram of AlphaFold2. [PDF]

Quant Biol
Li J, Zhu Z, Song C.
europepmc   +1 more source

Analog computer simulation of sampled-data systems

, 1962
The electronic analog computer is widely used to simulate most types of automatic control systems, Only a limited amount of work has been reported, however, involving analog computer simulation of sampled-data systems, This is to be expected since such ...
Dennison, Byron Lee
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Intersample vibrations in sampled-data mechanical systems

Motion control tasks of mechanical systems are usually realized through sampled-data systems, where the continuous-time plant is controlled by a discrete-time control law.
Haba, Tamás, Budai, Csaba
core   +1 more source

A generalized lineage nomenclature for viral genomic epidemiology. [PDF]

Nat Microbiol
Colquhoun R, Hinrichs AS, Hill V, Ruis C, Roemer C, Pybus OG, Rambaut A, O'Toole Á.   +7 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Comparative Analysis of Algorithms for Extracting Frames from Unexplored Regions in Molecular Dynamics Simulations. [PDF]

ACS Omega
Nagare A, Wagh S, Kotipalli A, Koulgi S, Jani V, Achalere A, Kale M, Sonavane U.   +7 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Soil organic carbon stocks, litter decomposition, and soil macrofauna diversity across contrasting land uses within a dual-purpose cattle farm in the Colombian Amazonian foothills. [PDF]

PLoS One
Narváez-Herrera JP, Angulo-Arizala J, Barragán-Hernández WA, Mavisoy-Muchavisoy H, Riascos-Vallejos AR, Mahecha-Ledesma L.   +5 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source