Results 201 to 210 of about 374,401 (266)

Application of Quantitative PCR (qPCR) for the Detection of Psittacine Beak and Feather Disease Virus (PBFDV) in Air Conditioning Systems: A Model Study from a Veterinary Hospital in Thailand. [PDF]

Vet Sci
Lorsunyaluck B, Charachit J, Putsetkun S, Pumipuntu N.   +3 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Genomic Epidemiology of Antibiotic-Resistant Bacteria Sampled from Metropolitan Wastewater. [PDF]

Microorganisms
Deslouches JT, Raabe NJ, Mills EG, Fleres G, Wallace NR, Yassin MH, Van Tyne D.   +6 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Beyond Classical Force Fields: Physics-Driven Assessment of the Grappa Machine-Learned Force Field on the FoldBind Dataset. [PDF]

Chemphyschem
Ranaweera I, Perez A.
europepmc   +1 more source

Evidence of Pervasive Legacy of Land Use Change on Dung Beetles in Central European Grazed Grasslands. [PDF]

Ecol Evol
Glatzhofer E, Lenzner B, Schernhammer T, Essl F.   +3 more
europepmc   +1 more source

Comparison of Protein-Glycosaminoglycan Interactions in ff14sb/GLYCAM06j-1 and CHARMM36m Force Fields. [PDF]

J Chem Inf Model
Bojarski KK, Wesołowski PA, Dewan D, Dziadek ŁJ, Neuman V, Brooks BR, Czub J, Zacharias M, Sieradzan AK, Wales DJ.   +9 more
europepmc   +1 more source

Distance-Restraint-Guided Diffusion Models for Sampling Protein Conformational Changes and Ligand Dissociation Pathways. [PDF]

J Chem Theory Comput
Hori T, Moriwaki Y, Ishitani R.
europepmc   +1 more source

A binary-related origin mediated by environmental conditions for blue straggler stars. [PDF]

Nat Commun
Ferraro FR, Lanzoni B, Vesperini E, Dalessandro E, Cadelano M, Pallanca C, Beccari G, Nardiello D, Libralato M, Piotto G.   +9 more
europepmc   +1 more source

How nature discovers rare Turing islands: Exploration by common limit cycles. [PDF]

Proc Natl Acad Sci U S A
Kim S, Matas-Gil A, Endres RG.
europepmc   +1 more source