Results 61 to 70 of about 1,812,833 (310)

A system for collecting and analyzing experience sampling data [PDF]

open access: yesBehavior Research Methods, 2018
Online and sensor technologies promise to transform many areas of psychological enquiry. However, collecting and analyzing this data is challenging. In this paper, we introduce the unforgettable.me experience sampling platform. unforgettable.me includes an app that can collect image, GPS, accelerometry and audio data in a continual fashion and upload ...
Simon Dennis   +4 more
openaire   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Robust Asynchronous Sampled-Data Control Design for Nonlinear Systems with Actuator Failures

open access: yesApplied Sciences, 2017
This paper presents a recent self-sampled-data control algorithm applied to nonlinear systems with actuator failures. Our approach uses the linear model of a given nonlinear system, and based on a granted actuator fault observer method, an asynchronous ...
Leonardo Acho, Pablo Buenestado
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The L∞/L2 Hankel operator/norm of sampled-data systems [PDF]

open access: yes, 2018
This paper is concerned with the Hankel operator and the Hankel norm of sampled-data systems. Even though these systems are intrinsically periodically time-varying, no studies have taken this important feature into account in the treatment of the Hankel ...
Kim, Hoon Jung   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sampled-data output feedback control for nonlinear uncertain systems using predictor-based continuous-discrete observer

open access: yes, 2022
In this article, we investigate the problem of sampled-data robust output feedback control for a class of nonlinear uncertain systems with time-varying disturbance and measurement delay based on continuous-discrete observer.
Jun Yang (4410343)   +3 more
core   +1 more source

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