Results 71 to 80 of about 1,812,833 (310)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Characterization of frequency drift of sampled-grating DBR laser module under direct modulation [PDF]
The authors demonstrate the drift in frequency of a static sampled-grating distributed Bragg reflector (SG DBR) laser module when it is subjected to direct modulation.
Anandarajah, Prince M. +13 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The problem of sampled-data observer design is addressed for a class of state- and parameter-affine nonlinear systems. The main novelty in this class lies in the fact that the unknown parameters enter the output equation and the associated regressor is ...
Schoukens, Maarten +7 more
core +1 more source
In this paper, a tractable sampled-data controller synthesis method is proposed for linear time-invariant plants that gives guarantees for stability and performance of the closed-loop system in terms of the H ∞- and H 2-norm.
Donkers, M.C.F. (Tijs) +1 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Sampled-data fuzzy controller for continuous nonlinear systems
The sampled-data fuzzy control of nonlinear systems is presented. The consequents of the fuzzy controller rules are linear sampled-data sub-controllers. As a result, the fuzzy controller is a weighted sum of some linear sampled-data sub-controllers that ...
Bingo Wing-Kuen Ling (14869390) +1 more
core +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

