Results 111 to 120 of about 31,882,609 (201)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Improved Sampled-Data Consensus Control for Multi-Agent Systems via Delay-Incorporating Looped-Functional

Mathematics
This paper addresses the problem of achieving consensus control for homogeneous multi-agent systems (MASs) under aperiodic sampled data and communication delays.
Khanh Hieu Nguyen, Sung Hyun Kim
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Stabilization of Neutral Time-Delay Systems With Actuator Saturation via a Sampled-Data Control Approach

IEEE Access
This paper considers the stabilization problem for neutral time-delay systems with actuator saturation under a sampled-data controller. For the actuator saturation, the saturation nonlinearity is represented as the convex combination of the state ...
Seok Young Lee, Junmin Park
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Sampled‐data‐based H∞ load frequency control for power systems with wind power

IET Renewable Power Generation
Load disturbances, the intermittent generation of wind power, and the uncertainty of sampling period will significantly affect the frequency stability of power system.
Shi‐Gang Qin, De‐Shun Liu, Hong‐Hai Lian   +2 more
doaj   +1 more source

Sampled-data synchronization control for chaotic neural networks subject to actuator saturation

, 2017
In this paper, the sampled-data control is applied to synchronize chaotic neural networks subject to actuator saturation. By employing a time-dependent Lyapunov functional that captures the characteristic information of actual sampling pattern, we derive
Honglei Xu (23287432), Kok Lay Teo (10892537), Y. He (9185), Hong-Bing Zeng (23438659), Wei Wang (17594)   +4 more
core  

Sampled-data output feedback control for nonlinear uncertain systems using predictor-based continuous-discrete observer

, 2022
In this article, we investigate the problem of sampled-data robust output feedback control for a class of nonlinear uncertain systems with time-varying disturbance and measurement delay based on continuous-discrete observer.
Jun Yang (4410343), Zhigang Zeng (3191088), Jiankun Sun (1879993), Huiming Wang (3023742)   +3 more
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source