Results 51 to 60 of about 7,676,917 (278)
Spinal Accessory Nerve Duplication – A Rare Anatomical Consternation During Neck Dissectio
Asian Pacific Journal of Cancer Care, 2021 Prevention of the spinal accessory nerve (SAN) is an indispensable aspect of the functional neck dissection surgery to avoid highly disabling shoulder syndrome postoperatively.
Rohit Jindal +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Tratamiento de la colusión en la contratación pública: una visión del caso colombiano
Revista de Derecho, 2014 La colusión, entendida como un pacto ilícito en daño a tercero, la cual se da en los procesos de contratación pública, es un acuerdo anticompetitivo sancionado por el numeral 9 del artículo 47 del Decreto 2153 de 1992, y más recientemente por la Ley 1474
Camilo Ernesto Ossa Bocanegra
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
College of San Mateo Mathematics and Science Teacher Education Program: A Bay Area Collaborative for Excellence in Teacher Preparation with San Jose State University and San Francisco State University [PDF]
, 1998 The College of San Mateo (CSM), a community college serving the San Mateo County area of California, is part of a collaborative effort in the San Francisco Bay Area to improve mathematics and science teacher preparation.
Tonini, C.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Uso del agua en cuencas hídricas interprovinciales
Revista Jurídica AustralEste trabajo analiza el voto en mayoría de las sentencias del 20 de diciembre de 2017 y del 16 de julio de 2020 de la Corte Suprema de Justicia de la Nación (CSJN) en la causa La Pampa, Provincia de c/Mendoza, Provincia de s/ uso de aguas (Fallos: 340 ...
Carlos Sánchez Mas
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source