Results 21 to 30 of about 224,524 (254)
SPI-7: Salmonella’s Vi-Encoding Pathogenicity Island
Salmonella Pathogenicity Island-7 (SPI-7) is a large, mosaic, genetic island, found in several serovars of Salmonella enterica subsp. enterica associated with systemic disease.
Helena M. B. Seth-Smith
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This poster beautifully illustrates the process and importance of Sanger sequencing. Developed by Diego Estrada-Rivadeneyra, it won one of the three 50th anniversary science communication competition prizes.
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Optimization in Sanger sequencing
The main objective of this paper is to solve the optimization problem that is associated with the classification of DNA samples in PCR plates for Sanger sequencing. To achieve this goal, we design an integer linear programming model. Given that the real instances involve the classification of thousands of samples and the linear model can only be solved
Luisa Carpente +3 more
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Prognostic stratification is critical for making therapeutic decisions and maximizing survival of patients with acute myeloid leukemia. Advances in the genomics of acute myeloid leukemia have identified several recurrent gene mutations whose prognostic ...
Niccolò Bolli +17 more
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Whole-exome sequencing improves genetic testing accuracy in pulmonary artery hypertension
Sanger sequencing, the traditional “gold standard” for mutation detection, has been wildly used in genetic testing of pulmonary artery hypertension (PAH). However, with the advent of whole-exome sequencing (WES), few studies have compared the accuracy of
Xiaofang Zeng +9 more
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Background: BRAF V600E mutation has been confirmed as a significant molecular indicator for the diagnosis and prognosis of papillary thyroid carcinoma (PTC).
Adhitya Bayu Perdana +3 more
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Identification of rare thalassemia variants using third-generation sequencing
Routine PCR, Sanger sequencing, and specially designed GAP-PCR are often used in the genetic analysis of thalassemia, but all these methods have limitations.
Qin Liu +11 more
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For sequence by dideoxy-method using the ABI3130 platform (Applied Biosystems, USA) and specific primers.
Lívia Sacchetto, Izabela M Rezende
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Knowledge of host associations of blood-feeding vectors may afford insights into managing disease systems and protecting public health. However, the ability of methods to distinguish bloodmeal sources varies widely.
Sujata Balasubramanian +16 more
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