Results 1 to 10 of about 2,252,648 (185)

JAK Inhibitors for Treatment of SAPHO Syndrome: A Systematic Review of 72 Cases. [PDF]

ACR Open Rheumatol
Objective Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome usually involves bones, joints, and skin. Due to a lack of known pathogenesis and clinical trials, there is no standard treatment of SAPHO syndrome.
Fazeli P, Bahramian S, Farahmand K, Ghoshouni H, Farahmand Y, Soheili A, Bagheri L, Memari H, Feyzi A, Vahabi SM.   +9 more
europepmc   +4 more sources

Coexistence of SAPHO syndrome and IgG4-related disease with Upadacitinib. [PDF]

Clin Transl Immunology
Objectives To describe the first reported case of coexisting Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) syndrome and IgG4‐related disease (IgG4‐RD) and to evaluate the therapeutic response to Upadacitinib.
Zhou H, Zhao X, Chen R, Wang T, Zhuang Y, Liu Y.   +5 more
europepmc   +4 more sources

Evaluation of tonsillectomy in the treatment of SAPHO syndrome: past evidence and future directions. [PDF]

Front Med (Lausanne)
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare aseptic inflammatory clinical syndrome characterized by widespread skin lesions and bone-joint lesions.
Gan WY, Ren BH, Zhang QP, Wang Y.
europepmc   +3 more sources

Upadacitinib in the treatment of SAPHO syndrome: a case report. [PDF]

Front Immunol
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare autoinflammatory disease, is usually defined by musculoskeletal symptoms and cutaneous manifestations.
Yang Y, Sun Z, Ge Y.
europepmc   +3 more sources

The role of cytokines in the pathogenesis of SAPHO syndrome. [PDF]

Front Immunol
SAPHO syndrome is a complex inflammatory disorder affecting the skin and bones, characterized by osteomyelitis, acne, and pustulosis. Cytokines play a pivotal role in the pathogenesis of SAPHO syndrome, especially in inflammatory responses and immune ...
Yang Y, Chen Q, Zhong W.
europepmc   +3 more sources

Postpartum lumbopelvic pain could be SAPHO syndrome: a case report. [PDF]

Front Immunol
BackgroundSynovitis–acne–pustulosis–hyperostosis–osteitis (SAPHO) syndrome is a rare autoimmune disorder. The involvement of spinal and sacroiliac joint in SAPHO syndrome closely resembles the manifestations of postpartum lumbopelvic pain (LPP).Case ...
Weiwei Z, Junhong Z, Rong Z.
europepmc   +3 more sources

What Is New and What Is Next for SAPHO Syndrome Management: A Narrative Review. [PDF]

J Clin Med
Synovitis–acne–pustulosis–hyperostosis–osteitis (SAPHO) syndrome is a rare disease characterized by a sterile inflammatory osteitis and/or arthritis associated with a wide range of dermatological manifestations, such as acne, palmoplantar pustulosis, and
Ferraioli M, Levani J, De Luca R, Matucci-Cerinic C, Gattorno M, Guiducci S, Bellando Randone S, Chimenti MS.   +7 more
europepmc   +4 more sources

Enteropathic SAPHO Syndrome in Ulcerative Colitis Responsive to Bisphosphonates. [PDF]

Case Rep Rheumatol
SAPHO syndrome, a rare inflammatory disorder of bone, joints, and skin, is named based on the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis.
Phillipps J, Mumtaz S, Valecha J, Stanborough RO, Berianu F, Abate E, Majithia V.   +6 more
europepmc   +3 more sources

Therapeutic approaches for SAPHO syndrome from the perspective of pathogenesis: a review of the literature. [PDF]

Front Immunol
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare autoinflammatory disease characterized by cutaneous manifestations and osteoarticular damage.
Wang Y, Gu M, Zheng Z, Jiang H, Han L, Huang H, Wu Y, Li C.   +7 more
europepmc   +3 more sources

Awareness of the Risk of Paradoxical Psoriasis in Patients with SAPHO Syndrome Undergoing Treatment with Secukinumab: A Case Series. [PDF]

J Inflamm Res
Cheng Xu,* Xiayan Xu,* Yongmei Han Department of Rheumatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongmei Han ...
Xu C, Xu X, Han Y.
europepmc   +3 more sources