Conclusions about a link between SAPHO syndrome, IgA nephropathy and dental amalgams can only be drawn after extensive analysis. [PDF]
Comment on “Dental amalgam associated with SAPHO syndrome and IgA nephropathy: a case report and literature review” by Cai et al. (2025)
Delrieu J +3 more
europepmc +2 more sources
SAPHO syndrome with a purely osteolytic form: A case report. [PDF]
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare, chronic autoinflammatory disorder that can present with a constellation of cutaneous and osteoarticular symptoms.
Kakiuchi A +7 more
europepmc +2 more sources
Current and future advances in practice: SAPHO syndrome and chronic non-bacterial osteitis (CNO). [PDF]
Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare, underdiagnosed disease with a wide clinical spectrum. Sterile bone inflammation, predominantly of the anterior chest, and skin manifestations (palmoplantar pustulosis ...
Furer V +4 more
europepmc +2 more sources
Challenges in Diagnosing SAPHO Syndrome: A Multidisciplinary Perspective. [PDF]
SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis syndrome) is a systemic inflammatory disease characterized by a combination of both osteoarticular and dermatological manifestations.
Zahid M, Vishwanatham V, Nasir I.
europepmc +2 more sources
Coexistence of adult-onset Still's disease and SAPHO syndrome. [PDF]
SAPHO syndrome and adult-onset Still’s disease (AOSD) are both rare polygenic auto-inflammatory diseases. SAPHO syndrome was initially described by the rheumatologist Chamot in 1987 and is characterized by osteitis, synovitis, bone hypertrophy ...
Wang Y +6 more
europepmc +2 more sources
Successful Treatment of Refractory Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome With Tofacitinib: A Case Report. [PDF]
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is primarily manifested by persistent inflammation affecting the musculoskeletal system and the skin. The treatment of SAPHO syndrome remains a challenge.
Alhayali M.
europepmc +2 more sources
The challenging diagnosis of synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome: A rare case report. [PDF]
Considered rare, the synovitis–acne–pustulosis–hyperostosis–osteitis (SAPHO) syndrome is a distinct clinical entity, associating skin manifestations and osteoarticular symptoms.
El Harras Y +4 more
europepmc +2 more sources
Successful Treatment of Refractory Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis (SAPHO) Syndrome with Baricitinib, a Janus Kinase Inhibitor. [PDF]
Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare immune-mediated inflammatory disease, poses diagnostic and therapeutic challenges owing to its multi-system involvement, high heterogeneity, and lack of specific laboratory ...
Yang J, Yuan C, Zhou S, Teng Z, Li M.
europepmc +2 more sources
Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report [PDF]
Introduction Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disorder. The etiology remains unknown and the treatment is still empirical.
Komiya Koichiro +6 more
doaj +3 more sources
Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO) Syndrome Mimicking Bone Metastases in the Spine: A Presentation of Two Cases and Literature Review. [PDF]
Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare disorder of unknown etiology with heterogeneous clinical manifestations. We describe two cases of patients diagnosed with SAPHO syndrome mimicking spinal bone metastases.
Rolemberg Dantas FL +4 more
europepmc +2 more sources

