Results 71 to 80 of about 9,220 (186)

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, Volume 208, Issue 5, Page 1713-1723, May 2026.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Beyond Rotavirus: Persistence of Norovirus, Adenovirus, and Astrovirus in Paediatric Gastroenteritis in the Republic of Congo After Vaccine Introduction

Journal of Medical Virology, Volume 98, Issue 4, April 2026.
ABSTRACT Despite the introduction of rotavirus vaccines, gastroenteritis remains a major cause of paediatric morbidity and mortality in the Republic of Congo. This study investigated the prevalence and genetic diversity of non‐rotavirus enteric viruses including norovirus (NoV), adenovirus (AdV), and astrovirus (AstV) ten years after the introduction ...
Cedeche Lebraiche Durain Mboungou, Claujens Chastel Mfoutou Mapanguy, Do Duc Anh, Jeannhey Christevy Vouvoungui, Alain Maxime Mouanga, Vivaldie Mikounou Louya, Emmanuel Seun Kupoluyi, Raoul Ampa, Thirumalaisamy P. Velavan, Francine Ntoumi   +9 more
wiley   +1 more source

Sapovirus genotype distribution among cases and healthy controls. [PDF]

, 2017
Sapovirus genotype distribution among cases and healthy controls.
Novalene Goklish (3612554), Katherine L. O’Brien (462225), Raymond Reid (462224), Umesh Parashar (432020), Jan Vinjé (2851898), Mathuram Santosham (174287), Lindsay R. Grant (462217), Robert C. Weatherholtz (462223)   +7 more
core   +1 more source

Human sapovirus GI.2 and GI.3 from children with acute gastroenteritis in northern Brazil

Memorias do Instituto Oswaldo Cruz, 2019
Human sapoviruses (HSaV) are considered important causative agents of acute gastroenteritis in humans worldwide. However, knowledge of the genetic characteristics of the whole genome of HSaV in Brazil is limited.
Audrey Cilli, Adriana Luchs, Elcio Leal, Danielle Gill, Flavio Augusto de Pádua Milagres, Shirley Vasconcelos Komninakis, Rafael Brustulin, Maria da Aparecida Rodrigues Teles, Márcia Cristina Alves Brito Sayão Lobato, Rogério Togisaki das Chagas, Maria de Fátima Neves dos Santos Abrão, Cassia Vitória de Deus Alves Soares, Xutao Deng, Eric Delwart, Ester Cerdeira Sabino, Antonio Charlys da Costa   +15 more
doaj   +1 more source

Prevalence and Genetic Characterisation of Human Sapovirus from Children with Diarrhoea in the Rural Areas of Vhembe District, South Africa, 2017–2020

Viruses, 2021
Diarrhoeal disease is considered an important cause of morbidity and mortality in developing areas, and a large contributor to the burden of disease in children younger than five years of age.
Mpho Magwalivha, Jean-Pierre Kabue Ngandu, Afsatou Ndama Traore, Natasha Potgieter   +3 more
doaj   +1 more source

Real‐world benefits and tolerability of trofinetide for the treatment of Rett syndrome: The LOTUS study

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 407-417, March 2026.
This original article is commented on by Kaufmann on pages 308–309 of this issue. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70051 Abstract Aim To describe the real‐world effects of trofinetide in individuals with Rett syndrome (RTT) using the 18‐month follow‐up analysis of the LOTUS study.
Louise Cosand, Haya Mayman, Jenny Downs, Victor Abler   +3 more
wiley   +1 more source

Percent of enteric virus co-infections with norovirus or sapovirus. [PDF]

, 2017
Percent of enteric virus co-infections with norovirus or sapovirus.
Novalene Goklish (3612554), Katherine L. O’Brien (462225), Raymond Reid (462224), Umesh Parashar (432020), Jan Vinjé (2851898), Mathuram Santosham (174287), Lindsay R. Grant (462217), Robert C. Weatherholtz (462223)   +7 more
core   +1 more source

Immune‐Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff, F. El‐Morabit, M. Löwenberg   +2 more
wiley   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Sapovirus translation requires an interaction between VPg and the cap binding protein eIF4E. [PDF]

, 2014
UNLABELLED: Sapoviruses of the Caliciviridae family of small RNA viruses are emerging pathogens that cause gastroenteritis in humans and animals. Molecular studies on human sapovirus have been hampered due to the lack of a cell culture system.

core   +2 more sources