Results 31 to 40 of about 21,278 (246)

The beta-isoform of neuronal nitric oxide synthase (nNOS) lacking the PDZ domain is localized at the sarcolemma [PDF]

, 2011
In skeletal muscles, the expression of neuronal NO synthase (nNOS) isoforms is uncharacterized at the protein level. We therefore conducted epitope mapping with anti-peptide-antibodies.
Huber-Abel, Felicitas A., Hans Hoppeler, Schläppi, Simon, Huber-Abel, Felicitas A, Hoppeler, Hans, Oliver Baum, Weichert, Alexander, Simon Schläppi, Felicitas A. Huber-Abel, Zakrzewicz, Andreas, Baum, Oliver, Andreas Zakrzewicz, Alexander Weichert   +12 more
core   +1 more source

Promising therapeutic approaches of utrophin replacing dystrophin in the treatment of Duchenne muscular dystrophy

Fundamental Research, 2022
Duchenne muscular dystrophy (DMD) is a serious genetic neuromuscular rare disease that is prevalent and caused by the mutation/deletion of the X-linked DMD gene that encodes dystrophin.
Ruo Wu, Yafeng Song, Shiwen Wu, Yongchang Chen   +3 more
doaj   +1 more source

Costamere remodeling with muscle loading and unloading in healthy young men [PDF]

, 2013
Costameres are mechano-sensory sites of focal adhesion in the sarcolemma that provide a structural anchor for myofibrils. Their turnover is regulated by integrin-associated focal adhesion kinase (FAK).
Erskine, Robert M., Seynnes, Olivier R., Simunic, B, Narici, MV, Flück M., Pisot, R, Flück, M., Rittweger J., Rittweger, Joern, Flueck, M, Narici M. V., Narici, Marco, Narici, Marco V., Flück, Martin, Seynnes O. R., Erskine, Robert, Li R., Rittweger, Jörn, Rittweger, J, Pisot, Rado, Seynnes, Olivier R, Seynnes, OR, Pišot R., Seynnes, Olivier, Li, Ruowei, Erskine, Robert M, Narici, Marco V, Erskine, RM, Šimunič B., Narici, Marco Vincenzo, Simunic, Bostjan, Erskine R. M., Li, R   +32 more
core   +1 more source

Massage increases satellite cell number independent of the age‐associated alterations in sarcolemma permeability

Physiological Reports, 2019
Massage is a widely accepted manual therapy used to modulate the inflammatory response of muscle and restore function, but prolonged compression of muscle potentially causes overt injury and damage to muscle fibers.
Emily R. Hunt, Amy L. Confides, Sarah M. Abshire, Esther E. Dupont‐Versteegden, Timothy A. Butterfield   +4 more
doaj   +1 more source

Neuronal nitric oxide synthase localizes through multiple structural motifs to the sarcolemma in mouse myotubes [PDF]

, 2000
In skeletal muscle, neuronal nitric oxide synthase is localized at the sarcolemma in association with the dystrophin glycoprotein complex (DGC). The nNOS N-terminal 231 amino acids comprise a PDZ domain (residues 1–100) and a β-hairpin finger loop ...
Padre, Roanna C, Kimberley E Burzynski, Roanna C Padre, Ahmed Abdelmoity, James T Stull, Kim S Lau, Burzynski, Kimberley E, Stull, James T, Lau, Kim S, Abdelmoity, Ahmed   +9 more
core   +1 more source

The role of calcium at the sarcolemma in the control of myocardial contractility [PDF]

, 1987
The importance of sarcolemmal-bound calcium (Ca) in the control of contraction in mammalian myocardium is indicated by the following results. The curve that relates [Ca]o (from 50 μM to 10 mM) to force development and that which relates [Ca]o to Ca ...
G. A. Langer
core   +1 more source

Characterisation of the canine cardiac sarcolemma in experimental myocardial ischemia [PDF]

, 1997
The cardiac sarcolemma was characterized in 13 normal and 11 ischemic dog hearts by enzyme analysis and compositional assays. Significant decreases in the activities of the sodium-potassium and calcium pumps and structural compositional disturbances were
Netticadan, T. J., Nair, K. G., Ashavaid , T. F.   +2 more
core   +2 more sources

A Sarcoplasmic Reticulum Localized Protein Phosphatase Regulates Phospholamban Phosphorylation and Promotes Ischemia Reperfusion Injury in the Heart

JACC: Basic to Translational Science, 2017
Summary: Phospholamban (PLN) is a key regulator of sarcolemma calcium uptake in cardiomyocyte; its inhibitory activity to sarcolemma-endoplasmic reticulum calcium ATPase is regulated by phosphorylation.
Toru Akaike, MD, PhD, Na Du, MD, PhD, Gang Lu, PhD, Susumu Minamisawa, MD, PhD, Yibin Wang, PhD, Hongmei Ruan, MD, PhD   +5 more
doaj   +1 more source

Fine structure of the intercalated disc and cardiac junctions in the black widow spider Latrodectus mactans

Applied Microscopy, 2020
Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates.
Yan Sun, Seung-Min Lee, Bon-Jin Ku, Myung-Jin Moon   +3 more
doaj   +1 more source

Ca2+-ATPase distributes differently in cardiac sarcolemma than dihydropyridine receptor α1 subunit and Na+/Ca2+ exchanger [PDF]

, 1994
We have investigated the distribution of the sarcolemmal Ca2+ transporters in hamster and dog ventricular myocytes by immunocytochemical and membrane fractionation techniques.
Takahashi, Masami, Masami Takahashi, Hanada, Hironori, Munekazu Shigekawa, Yuko Iwata, Iwata, Yuko, Shigekawa, Munekazu, Hironori Hanada   +7 more
core   +1 more source