Results 91 to 100 of about 18,467 (180)
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki +13 more
wiley +1 more source
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima +8 more
wiley +1 more source
ABSTRACT Aim To explore challenges parents of children with cancer encounter while providing complex medical care at home. Methods Design: Cross‐sectional convergent mixed‐methods study. Instruments: Questionnaire and open interviews that mirrored and complemented each other.
Rachel Klausner Shyman +5 more
wiley +1 more source
Ethical considerations of genetic and genomic testing in pediatric oncology: A narrative review
Abstract Genomics—and genomic testing in particular—has transformed oncology, facilitating both targeted therapies and personalized care. In pediatric oncology, unique clinical and ethical considerations arise. Compared with adults, children and adolescents are affected by more limited evidence regarding test performance, variant interpretation, and ...
Brittany L. Greene, Jonathan M. Marron
wiley +1 more source
ABSTRACT Background Sentinel lymph node (SLN) biopsy is a critical staging tool in skin and soft tissue cancers. Although technetium lymphoscintigraphy is the most common adjunct, indocyanine green (ICG) demonstrates a promising alternative in pediatric, adolescent, and young adult (AYA) skin and soft tissue cancers. Methods and Objectives Evaluate the
Sophia M. V. Schermerhorn +34 more
wiley +1 more source
Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma
Ewing sarcoma is a pediatric bone and soft tissue tumor treated with chemotherapy, radiation, and surgery. Despite intensive multimodality therapy, ~50% patients eventually relapse and die of the disease due to chemoresistance.
Le Yu +6 more
doaj +1 more source
Ewing′s Sarcoma of the Ramus of Mandible - Report of a Case
Ewing′s Sarcoma is a highly lethal round cell sarcoma of unknown etiology that was first described by ′James Ewing′ in 1921. Ewing′s sarcoma is one of the most aggressive bone tumors known and accounts for 4-7% of primary bone malignancies.
Mubeen +2 more
doaj
Ewing sarcoma of the uterus: A case report
A case is described of Ewing sarcoma of the uterus, an atypical presentation of an already rare cancer.A 55-year-old woman presented with abdominal pain, abnormal uterine bleeding and a uterine mass that measured 11 × 10 × 14.5 cm and demonstrated ...
Zeynep Tek +4 more
doaj +1 more source
M E, Horowitz, M G, Tsokos, T F, DeLaney
openaire +2 more sources
Myc and Skp2 overexpression promotes p27 ubiquitination and degradation in Ewing Sarcoma. [PDF]
Kubota Y +4 more
europepmc +1 more source

