Results 241 to 250 of about 42,993 (322)

Ablation of Slc26a6 Mitigates Myocardial Ischemia/Reperfusion Injury. [PDF]

Biomedicines
Thai PN, Ren L, Diloretto DA, Trinh P, Timofeyev V, Zong N, Ngo RQ, Chiamvimonvat N, Zhang XD.   +8 more
europepmc   +1 more source

Morphological differences in myofibre size and shape: A comparative study of the soleus, gastrocnemius, triceps brachii and vastus lateralis in humans and mice

Journal of Anatomy, Volume 248, Issue 1, Page 126-139, January 2026.
Myofibre size and shape were investigated in functionally distinct muscles of humans and mice using ATPase histochemistry and immunofluorescence. In both species, soleus myofibres were found to be larger, more irregularly shaped, and more heterogeneous compared to other muscles. These findings may have implications for biomedical research and potential
Casper Soendenbroe, Rene B. Svensson, Bettina Mittendorfer, S. Peter Magnusson, Abigail L. Mackey, Jesper L. Andersen   +5 more
wiley   +1 more source

Microtubule forces drive nuclear damage in LMNA cardiomyopathy. [PDF]

Nat Cardiovasc Res
Amiad Pavlov D, Heffler J, Suay-Corredera C, Dehghany M, Shen KM, Zuela-Sopilniak N, Randell R, Uchida K, Jain R, Shenoy V, Lammerding J, Prosser B.   +11 more
europepmc   +1 more source

Simulation of Ca2+ Release from the Sarcoplasmic Reticulum with Three-Dimensional Sarcomere Model in Cardiac Muscle.

, 2002
Tsukasa Tameyasu
openalex   +2 more sources

Myo18b is essential for sarcomere assembly in fast skeletal muscle

Human Molecular Genetics, 2017
Joachim Berger, S. Berger, Mei Li, P. Currie   +3 more
semanticscholar   +1 more source

Lesion Formation in Cardiac Pulsed‐Field Ablation: Acute to Chronic Cellular Level Changes

Pacing and Clinical Electrophysiology, Volume 49, Issue 1, Page 32-42, January 2026.
ABSTRACT As pulsed‐field ablation (PFA) emerges as a promising therapy for atrial arrhythmias, an understanding of the cellular injury to cardiac tissue is critical to evaluating and interpreting results for each PFA system. This review aims to detail the mechanism of cell death for PFA, compare the cell death mechanism to thermal ablation modalities ...
Kara Garrott, Savannah Bifulco, David Ramirez, Brendan Koop   +3 more
wiley   +1 more source

Cellular and Molecular Mechanisms of Heart Failure and Sudden Cardiac Death in Hypertrophic Cardiomyopathy and Methods Used for Their Pathogenetic Correction. [PDF]

Biomedicines
Kakturskiy L, Belov Y, Mikhaleva L, Lysenko A, Gioeva Z, Tikhonova N, Gutyrchik N.   +6 more
europepmc   +1 more source

Aldehyde Dehydrogenase‐2 Alleviates Septic Myocardial Injury by Inhibiting Caspase‐11‐Mediated Noncanonical Pyroptosis

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Purpose The purpose of this study is to investigate the role of aldehyde dehydrogenase‐2 (ALDH2) in septic myocardial injury, focusing on noncanonical pyroptosis. Methods In vivo, C57BL/6J mice were divided into five groups: Sham, cecal ligation and puncture (CLP), CLP + Alda‐1 (ALDH2 agonist), Sham + dimethyl sulfoxide (DMSO, solvent control), and CLP 
Huan Liang, Yuying He, Yiren Wang, Rui Zhang, Mengjie Yu, Hongwei Ye, JiaHui Wang, Qin Gao, Vivek Pandey   +8 more
wiley   +1 more source

Myocardial disarray drives metabolic inefficiency in human cardiomyocytes. [PDF]

Commun Biol
Jouve C, Ruiz-Velasco A, Donnarumma E, Le Borgne R, Momken I, Pereira C, Seguret M, Vermersch E, Vimont E, Nemazanyy I, Bertrand L, Wai T, Verbavatz JM, Mericksay M, Hulot JS.   +14 more
europepmc   +1 more source

Low‐Dose Mavacamten Initiation in Obstructive Hypertrophic Cardiomyopathy: A Real‐World Study in China

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Aims To evaluate the real‐world efficacy and safety of low‐dose (2.5 mg) mavacamten initiation in Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM). Methods and Results This single‐center observational study (Zhongshan Hospital, China; Oct 2024–Apr 2025) enrolled 72 symptomatic oHCM patients (NYHA II/III, LVEF ≥ 55 ...
Wenlong Yang, Hui Shi, Rebecca Suchi Chang, Yin Zhang, A. Jixiang, Chunyu Wu, Juying Qian, Junbo Ge, Shuning Zhang, Baohui Xu   +9 more
wiley   +1 more source