Results 131 to 140 of about 19,099 (312)

Exam Preview Methods Are Associated With Improvements for the Experiences and Learning of College Science Students

Science Education, EarlyView.
ABSTRACT College science exams are an important and widespread marker for student progress toward technical careers. Predominantly enacted using traditional teaching practices, exams also represent an opportunity for significant improvement in higher education.
Benjamin L. Wiggins, Kerri Wingert, Gregory J. Crowther   +2 more
wiley   +1 more source

Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans

Integrative Zoology, EarlyView.
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong, Wenpei Xin, Zeyu Liu, Yami Zheng, Mengyi Huang, Hongguang Liu, Decai Lu, Wei Peng, Zhonge Hou   +8 more
wiley   +1 more source

Monitoring Cardiac Troponin Structural Changes using In-Situ Time-Resolved FRET: Implications on the Regulatory Roles of Cross-Bridges and Sarcomere Length [PDF]

, 2014
King‐Lun Li, Daniel Rieck, R. John Solaro, Wen‐Ji Dong   +3 more
openalex   +1 more source

Stretch Harmonizes Sarcomere Strain Across the Cardiomyocyte

, 2023
Jia Li, Joakim Sundnes, Yufeng Hou, Martin Laasmaa, Marianne Ruud, Andreas Unger, Terje R. Kolstad, Michael Frisk, Per Andreas Norseng, Limin Yang, Ingunn E. Setterberg, Estela Santos‐Alves, Michaeljohn Kalakoutis, Ole M. Sejersted, Johanna T. Lanner, Wolfgang A. Linke, Ida G. Lunde, Pieter P. de Tombe, William E. Louch   +18 more
openalex   +1 more source

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang, Chunlan Deng, Xiaogang Guo, Hui Yan   +3 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Fluid mechanics of sarcomeres as porous media.

Muscle contraction, both in skeletal and cardiac tissue, is driven by sarcomeres, the microscopic units inside muscle cells where thick myosin and thin actin filaments slide past each other.

core   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Cardiomyopathy mutations in the tail of beta cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes.

, 2013
It is unclear why mutations in the filament forming tail of myosin heavy chain (MHC) cause hypertrophic (HCM) or dilated (DCM) cardiomyopathy as these mutations should not directly affect contraction. To investigate this, we first investigated the impact
Wolny, M, Knight, P, Peckham, M, White, E, Colman, L, Colegrave, M   +5 more
core   +1 more source

Sarcomere ACTC1 and MYO18A serum expression levels detect acute cellular rejection in cardiac transplant patients [PDF]

, 2021
Luna Carrillo, Juan Carlos Triviño, Iolanda Lázaro, Luis Martínez‐Dolz, Manuel Portolés, Estefanía Tarazón, Esther Roselló‐Lletí   +6 more
openalex   +1 more source