Results 121 to 130 of about 17,660 (277)

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso, Monica Matuozzo, Mariapina Rocco, Seyed Hossein Hoseinifar, Ghasem Ashouri, Andrea Scaloni, Marina Paolucci, Chiara D'Ambrosio, Roberta Imperatore   +8 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Electrical Modalities in the Rehabilitation of Peripheral Nerve Injuries: State of the Literature and Current Clinical Applications

Muscle &Nerve, EarlyView.
ABSTRACT Peripheral nerve injuries (PNIs) are a common cause of long‐term motor and sensory disability despite advances in microsurgical repair. Functional recovery following PNI depends not only on axonal regeneration, but also on preservation of distal nerve pathways, maintenance of neuromuscular junction integrity, prevention of irreversible muscle ...
Sarah M. Smith, Kirsten M. Schlosser, Ranee Munaim, Stephanie H. Vu, JulieAnn H. Uh, Yusha K. Liu   +5 more
wiley   +1 more source

Beyond BMI: Genome‐Wide Associations of Visceral Fat, Fat Mass, and Fat‐Free Mass in Eastern Asian Populations

Obesity, EarlyView.
ABSTRACT Objective BMI is widely used to define obesity and may not capture heterogeneity in body fat distribution. Genetic studies of obesity have largely focused on BMI but not visceral fat and fat‐free mass, which is particularly limited in East Asian populations.
Hsin‐Ming Lu, Shun‐Jen Chang, Kuei‐Hau Luo, Yun‐Shiuan Chuang, Fu‐Wen Liang, Hung‐Yi Chuang   +5 more
wiley   +1 more source

Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)

ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang, Chunlan Deng, Xiaogang Guo, Hui Yan   +3 more
wiley   +1 more source

Exam Preview Methods Are Associated With Improvements for the Experiences and Learning of College Science Students

Science Education, EarlyView.
ABSTRACT College science exams are an important and widespread marker for student progress toward technical careers. Predominantly enacted using traditional teaching practices, exams also represent an opportunity for significant improvement in higher education.
Benjamin L. Wiggins, Kerri Wingert, Gregory J. Crowther   +2 more
wiley   +1 more source

Engineering In Vitro Models of Skeletal Muscle With Neuromuscular Junctions Using Hierarchical Micro‐Nano Biomaterials: Cooperative Effect of Adhesion Ligand Nanoclustering and Surface Anisotropy

Small, EarlyView.
This study investigates the cooperative effects of adhesive ligand distribution, density, and biomaterial morphology for innervated skeletal muscle tissue engineering. Ligand nanoclusters were created in aligned micropatterns by electrospinning of a RAFT‐synthesized polymer with controlled ligand presentation.
Shirin Nour, Kristy Swiderski, Sahar Salehi, Gordon S. Lynch, Andrea J. O'Connor, Greg G. Qiao, Daniel E. Heath   +6 more
wiley   +1 more source

Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans

Integrative Zoology, EarlyView.
Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong, Wenpei Xin, Zeyu Liu, Yami Zheng, Mengyi Huang, Hongguang Liu, Decai Lu, Wei Peng, Zhonge Hou   +8 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function

Communications Biology
UNC-89 is a giant sarcomeric M-line protein required for sarcomere organization and optimal muscle function. UNC-89 contains two protein kinase domains, PK1 and PK2, separated by an elastic region.
Yohei Matsunaga, Hiroshi Qadota, Nasab Ghazal, Leila Lesanpezeshki, Till Dorendorf, Jasmine C. Moody, Arnaud Ahier, Courtney J. Matheny, Siva A. Vanapalli, Steven Zuryn, Olga Mayans, Jennifer Q. Kwong, Guy M. Benian   +12 more
doaj   +1 more source