Results 91 to 100 of about 140,542 (289)

Developmental Changes in the Excitation–Contraction Mechanisms of the Ventricular Myocardium and Their Sympathetic Regulation in Small Experimental Animals

open access: yesJournal of Cardiovascular Development and Disease
The developmental changes in the excitation–contraction mechanisms of the ventricular myocardium of small animals (guinea pig, rat, mouse) and their sympathetic regulation will be summarized.
Shogo Hamaguchi   +4 more
doaj   +1 more source

The Ultrastructure of Developing Sarcoplasmic Reticulum

open access: yesJournal of Biological Chemistry, 1974
Developmental changes in the sarcoplasmic reticulum and surface membranes of chicken skeletal muscles were investigated by electron microscopy. A dominant feature of freeze-etched sarcoplasmic reticulum membranes isolated from adult animals is the presence of spherical intramembranous particles of 75 A apparent diameter which are more numerous on the ...
T W, Tillack, R, Boland, A, Martonosi
openaire   +2 more sources

Molecular cloning of cDNA encoding a 55-kDa multifunctional thyroid hormone binding protein of skeletal muscle sarcoplasmic reticulum

open access: yes, 1990
A cDNA clone encoding 55-kDa multifunctional, thyroid hormone binding protein of rabbit skeletal muscle sarcoplasmic reticulum was isolated and sequenced.
Burns, K.   +3 more
core   +1 more source

An investigation of NAADP-dependent Ca²⁺ signalling mechanisms in arterial smooth muscle [PDF]

open access: yes, 2007
Previous investigations on pulmonary artery smooth muscle cells have shown that nicotinic acid adenine dinucleotide diphosphate (NAADP) evokes highly localised intracellular Ca²⁺ bursts by mobilising thapsigargin-insensitive Ca²⁺ stores.
Kinnear, Nicholas P.
core   +2 more sources

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli   +6 more
wiley   +1 more source

Organelle Optogenetics: Direct Manipulation of Intracellular Ca2+ Dynamics by Light

open access: yesFrontiers in Neuroscience, 2018
As one of the ubiquitous second messengers, the intracellular Ca2+, has been revealed to be a pivotal regulator of various cellular functions. Two major sources are involved in the initiation of Ca2+-dependent signals: influx from the extracellular space
Toshifumi Asano   +4 more
doaj   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

open access: yesUroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega   +6 more
wiley   +1 more source

Impaired Sarcoplasmic Reticulum Calcium Uptake and Release Promote Electromechanically and Spatially Discordant Alternans: A Computational Study

open access: yes, 2016
Cardiac electrical dynamics are governed by cellular-level properties, such as action potential duration (APD) restitution and intracellular calcium (Ca) handling, and tissue-level properties, including conduction velocity restitution and cell–cell ...
Seth H. Weinberg
core   +1 more source

Increased energetic cost of movement reduces reproductive output in zebrafish at different temperatures and water flow rates

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Locomotion consumes a large proportion of individual energy budgets and may impose energetic constraints on other fitness‐related traits particularly under variable environmental conditions.
Miki Jahn, Frank Seebacher
wiley   +1 more source

Calcium sparks in arterial smooth muscle cells regulate vascular tone

open access: yesJournal of Biological Research, 2002
It is named Ca2+ sparks a local, rapid and transient Ca2+ release from sarcoplasmic reticulum (SR) by the opening of ryanodine-sensitive (RyR) channels. RyR channels localized in SR are found in all muscle cell types (cardiac, skeletal, smooth) and many
Maurizio Mandalà
doaj   +1 more source

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