Results 251 to 260 of about 17,855 (302)
THE ENZYMATIC HYDROLYSIS PRODUCTS OF SARIN
Canadian Journal of Biochemistry and Physiology, 1956 The hydrolysis of the powerful cholinesterase inhibitor, sarin, by a rat serum enzyme leads almost exclusively to isopropyl methylphosphonic acid, neither methylphosphonic acid nor hydrogen methylphosphonofluoridate being formed. When isopropyl methylphosphonic acid is administered to the intact rat, it is excreted unchanged in the urine.
F. C. G. Hoskin
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Journal of Molecular Spectroscopy, 2001
As part of an effort to examine the possibility of using molecular-beam Fourier-transform microwave spectroscopy to unambiguously detect and monitor chemical warfare agents, we report the first observation and assignment of the rotational spectrum of the nerve agent Sarin (GB) (Methylphosphonofluoridic acid 1-methyl-ethyl ester, CAS #107-44-8) at ...
A. R. Hight, Walker +6 more
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As part of an effort to examine the possibility of using molecular-beam Fourier-transform microwave spectroscopy to unambiguously detect and monitor chemical warfare agents, we report the first observation and assignment of the rotational spectrum of the nerve agent Sarin (GB) (Methylphosphonofluoridic acid 1-methyl-ethyl ester, CAS #107-44-8) at ...
A. R. Hight, Walker +6 more
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Biodegradation of neutralized Sarin
Biotechnology and Bioengineering, 1999This research investigated the biotransformation of IMPA, the neutralization product of the nerve agent Sarin, by a microbial consortia. As mandated by the Chemical Weapons Convention signed by 132 countries in 1993, all chemical warfare agents are to be destroyed within ten years of ratification.
Y, Zhang +4 more
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Refractoriness (Tachyphylaxis) to ‘Sarin’
Nature, 1962APART from experiments reported in 1954 by Barnes and Duff1, the occurrence of tachyphylaxis to poisons which act by inhibiting cholinesterase has been little publicized, although the phenomenon appears to offer possibilities as a means of investigating cholinergic function. The following is an account of a method which, in a proportion of experiments,
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Sensors to Detect Sarin Simulant
Critical Reviews in Analytical Chemistry, 2020This work presents a literature review concerning the construction, properties and application of different sensors used to detect dimethyl methylphonate (DMMP), which is the simulant of sarin. Sensors sensitive to mass are described, together with such sensors as: SAW, QCM, MEMS, also chemical capacitors, semiconductors, and field effect transistors.
Marcin Bielecki +2 more
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Sarin poisoning in Matsumoto, Japan
The Lancet, 1995A presumed terrorist attack with sarin occurred in a residential area of the city of Matsumoto, Japan, on June 27, 1994. About 600 residents and rescue staff were poisoned; 58 were admitted to hospitals, and 7 died. We examined clinical and laboratory findings of 264 people who sought treatment and the results of health examinations on 155 residents ...
H, Morita +8 more
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Southern Medical Journal, 2013
Given the current geopolitical tensions, the risk of a terrorist attack on the United States is constant and increasing. Chemical terrorism, specifically the use of nerve agents, has occurred in other nations. Because of the ease of manufacture, the ability to conceal them, and the lethality of these agents, they pose a potential threat as a weapon of ...
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Given the current geopolitical tensions, the risk of a terrorist attack on the United States is constant and increasing. Chemical terrorism, specifically the use of nerve agents, has occurred in other nations. Because of the ease of manufacture, the ability to conceal them, and the lethality of these agents, they pose a potential threat as a weapon of ...
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Sarin Poisoning on Tokyo Subway
Southern Medical Journal, 1997On the day of the disaster, 641 victims were seen at St. Luke's International Hospital. Among those, five victims arrived with cardiopulmonary or respiratory arrest with marked miosis and extremely low serum cholinesterase values; two died and three recovered completely. In addition to these five critical patients, 106 patients, including four pregnant
S, Ohbu +9 more
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Sarin-induced neuropathology in rats
Human & Experimental Toxicology, 1995Sarin, a highly toxic cholinesterase (ChE) inhibitor, administered at near 1 LD50 dose causes severe signs of toxic cholinergic hyperactivity in both the peripheral and central nervous systems (CNS). The present study evaluated acute and long-term neuropathology following exposure to a single LD50 dose of sarin and compared it to lesions caused by ...
T, Kadar +5 more
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