Results 11 to 20 of about 3,612 (205)
La colonisation par SARM [PDF]
médecine/sciences, 2008 Staphylococcus aureus est un pathogene important dans les infections humaines. Il a toujours pose de grands problemes therapeutiques car, des les annees 1970, des clones resistants aux antibiotiques, et notamment a la meticilline (SARM), se sont installes a l'hopital. Le portage nasal ainsi que la colonisation des patients par S.
Henri B. Drugeon
openaire +2 more sources
El tratamiento antibiótico óptimo para la neumonía por SARM: buscando "el Dorado"
Revista Electrónica de AnestesiaR, 2010 La neumonía por Staphylococcus aureus resistente a la meticilina (SARM) es una de las infecciones nosocomiales más comunes y está asociada con una elevada mortalidad y coste sanitario. De hecho, la tasa de mortalidad hospitalaria asociada con infecciones
Santiago Ernesto Denis, Emilio Maseda
doaj +4 more sources
Biomédica: revista del Instituto Nacional de Salud, 2014 Introducción. USA300 es un linaje genético que se encuentra en aislamientos de Staphylococcus aureus sensibles (SASM) y resistentes a meticilina (SARM).
Javier Antonio Escobar-Pérez +7 more
doaj +3 more sources
The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling. [PDF]
PLoS ONE, 2013 Sterile alpha and armadillo-motif containing protein (SARM), a highly conserved and structurally unique member of the MyD88 family of Toll-like receptor adaptors, plays an important role in innate immunity signaling and apoptosis.
Chad R Sethman, Jacek Hawiger
doaj +2 more sources
Molecules, 2023 Among anabolic agents, selective androgen receptor modulators (SARMs) represent a new class of potential drugs that can exhibit anabolic effects on muscle and bone with reduced side effects due to a tissue-selective mode of action.
Tristan Möller +4 more
doaj +2 more sources
MCBS (Molecular and Cellular Biomedical Sciences)Background: Orchidectomy is a surgical androgen deprivation therapy (ADT) for prostate cancer patients to achieve castrate testosterone levels. Selective androgen receptor modulators (SARMs) are used to mitigate the adverse effects of ADT, including ...
Taufiq Nur Budaya +8 more
doaj +2 more sources
Enzymatic Prenylation of Proteins and Peptides: From Cysteine S-Prenylation to Tryptophan-Selective Biocatalysis. [PDF]
ChemistryThis review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Fujinami D, Ozawa H, Ito S.
europepmc +2 more sources
Further Insights Into the Metabolism of LGD-4033 in Human Urine. Part 2. A New Minor Metabolite With Antagonistic Activity on the Androgen Receptor Can Indicate Recent Substance Intake. [PDF]
Drug Test AnalA novel early excreted minor metabolite of LGD‐4033 was detected and coded as M8. Its presence was evaluated as an indicator of recent substance intake versus end‐tail findings. Additionally, the agonist/antagonist properties of M8 and other selected LGD‐4033 metabolites on the androgen receptor (AR) were studied using in silico molecular docking and ...
Angelis YS +10 more
europepmc +2 more sources
Brazilian Journal of Infectious Diseases, 2022 Introdução: A vancomicina representa uma das principais ou, senão a primeira opção terapêutica para o tratamento de infecções causadas por Staphylococcus aureus resistentes à meticilina (SARM) em diversos serviços de saúde.
Juliana Oliveira da Silva +2 more
doaj +1 more source
Analecta Veterinaria, 2022 Se describe el resultado de la búsqueda de Staphylococcus aureus resistentes a meticilina (SARM) en la cavidad nasal de cerdos de cría intensiva, durante los años 2019 y 2021, con el objetivo de dar a conocer si existe circulación, en Argentina, de este
Gabriela Isabel Giacoboni +6 more
doaj +1 more source