Results 11 to 20 of about 11,053 (212)

Further Insights Into the Metabolism of LGD-4033 in Human Urine. Part 2. A New Minor Metabolite With Antagonistic Activity on the Androgen Receptor Can Indicate Recent Substance Intake. [PDF]

open access: yesDrug Test Anal
A novel early excreted minor metabolite of LGD‐4033 was detected and coded as M8. Its presence was evaluated as an indicator of recent substance intake versus end‐tail findings. Additionally, the agonist/antagonist properties of M8 and other selected LGD‐4033 metabolites on the androgen receptor (AR) were studied using in silico molecular docking and ...
Angelis YS   +10 more
europepmc   +2 more sources

New Insights Into the Evolution of Immune Adaptors in Murid Rodents. [PDF]

open access: yesEcol Evol
TIR domain‐containing adaptors were evolved under purifying selection in murine. Positively selected sites were identified in Mal and Myd88 genes. Reduced genetic diversity of each adaptor gene was observed in two rat populations. Shared polymorphisms were common phenomena in rat adaptors.
Su Q, She Z, Chen Y.
europepmc   +2 more sources

Annual Banned-Substance Review 18th Edition-Analytical Approaches in Human Sports Drug Testing 2024/2025. [PDF]

open access: yesDrug Test Anal
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Thevis M, Kuuranne T, Geyer H.
europepmc   +2 more sources

AVALIAÇÃO DO IMPACTO DOS VALORES DA CONCENTRAÇÃO INIBITÓRIA MÍNIMA PARA VANCOMICINA NO DESFECHO CLÍNICO DE PACIENTES COM INFECÇÃO DA CORRENTE SANGUÍNEA POR STAPHYLOCOCCUS AUREUS RESISTENTE A METICILINA

open access: yesBrazilian Journal of Infectious Diseases, 2022
Introdução: A vancomicina representa uma das principais ou, senão a primeira opção terapêutica para o tratamento de infecções causadas por Staphylococcus aureus resistentes à meticilina (SARM) em diversos serviços de saúde.
Juliana Oliveira da Silva   +2 more
doaj   +1 more source

Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users

open access: yesJournal of Xenobiotics, 2023
Selective Androgen Receptor Modulators (SARMs) are not FDA approved, and obtaining SARMs for personal use is illegal. Nevertheless, SARM use is increasingly popular amongst recreational athletes.
Jonathan D. Vignali   +7 more
doaj   +1 more source

Circulación de Staphylococcus aureus resistentes a meticilina y multirresistente, en granjas de cría porcina de Argentina

open access: yesAnalecta Veterinaria, 2022
Se describe el resultado de la búsqueda de Staphylococcus aureus resistentes a meticilina (SARM) en la cavidad nasal de cerdos de cría intensiva, durante los años 2019 y 2021, con el objetivo de dar a conocer si existe circulación, en Argentina, de este
Gabriela Isabel Giacoboni   +6 more
doaj   +1 more source

Evaluation of Sentinel-6 Altimetry Data over Ocean

open access: yesRemote Sensing, 2022
The Sentinel-6 Michael Freilich (S6-MF) satellite was launched on 21st November 2020. Poseidon-4, the main payload onboard S6-MF, is the first synthetic aperture radar (SAR) altimeter operating in an interleaved open burst mode.
Maofei Jiang, Ke Xu, Jiaming Wang
doaj   +1 more source

Necroptosis is SARMful to your health [PDF]

open access: yesJournal of Cell Biology, 2020
Necroptosis is a cell death pathway involved in inflammation and disease. In this issue, Ko et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) link SARM1, the executioner of Wallerian degeneration of axons, to necroptosis, revealing a unique form of axonal disassembly likely involved in neurodegenerative disorders.
openaire   +3 more sources

A selective androgen receptor modulator SARM‐2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys

open access: yesPharmacology Research & Perspectives, 2020
SARM‐2f a selective androgen receptor (AR) modulator, increases skeletal muscle mass and locomotor activity in rats. This study aimed to clarify its pharmacological effects in monkeys.
Megumi Morimoto   +2 more
doaj   +1 more source

Femtosecond laser ablation-ICP-mass spectrometry analysis of a heavy metallic matrix : determination of platinum group metals and gold in lead fire-assay buttons as a case study [PDF]

open access: yes, 2010
Owing to the shorter time interval during which energy is delivered to the sample material, femtosecond (fs) laser ablation is preferable over nanosecond laser ablation for metallic samples. In this project, the influence of various laser parameters-beam
Günther, Detlev   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy