Results 21 to 30 of about 3,612 (205)

New Insights Into the Evolution of Immune Adaptors in Murid Rodents. [PDF]

open access: yesEcol Evol
TIR domain‐containing adaptors were evolved under purifying selection in murine. Positively selected sites were identified in Mal and Myd88 genes. Reduced genetic diversity of each adaptor gene was observed in two rat populations. Shared polymorphisms were common phenomena in rat adaptors.
Su Q, She Z, Chen Y.
europepmc   +2 more sources

Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users

open access: yesJournal of Xenobiotics, 2023
Selective Androgen Receptor Modulators (SARMs) are not FDA approved, and obtaining SARMs for personal use is illegal. Nevertheless, SARM use is increasingly popular amongst recreational athletes.
Jonathan D. Vignali   +7 more
doaj   +1 more source

Annual Banned-Substance Review 18th Edition-Analytical Approaches in Human Sports Drug Testing 2024/2025. [PDF]

open access: yesDrug Test Anal
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Thevis M, Kuuranne T, Geyer H.
europepmc   +2 more sources

Evaluation of Sentinel-6 Altimetry Data over Ocean

open access: yesRemote Sensing, 2022
The Sentinel-6 Michael Freilich (S6-MF) satellite was launched on 21st November 2020. Poseidon-4, the main payload onboard S6-MF, is the first synthetic aperture radar (SAR) altimeter operating in an interleaved open burst mode.
Maofei Jiang, Ke Xu, Jiaming Wang
doaj   +1 more source

Necroptosis is SARMful to your health [PDF]

open access: yesJournal of Cell Biology, 2020
Necroptosis is a cell death pathway involved in inflammation and disease. In this issue, Ko et al. (2020. J. Cell Biol.https://doi.org/10.1083/jcb.201912047) link SARM1, the executioner of Wallerian degeneration of axons, to necroptosis, revealing a unique form of axonal disassembly likely involved in neurodegenerative disorders.
openaire   +3 more sources

A selective androgen receptor modulator SARM‐2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys

open access: yesPharmacology Research & Perspectives, 2020
SARM‐2f a selective androgen receptor (AR) modulator, increases skeletal muscle mass and locomotor activity in rats. This study aimed to clarify its pharmacological effects in monkeys.
Megumi Morimoto   +2 more
doaj   +1 more source

Comportamento dos sistemas Sm-Nd e Rb-Sr da seqüência acamadada máfico-ultramáfica Ribeirão dos Motas (arqueano), cráton São Francisco Meridional: evidências de enriquecimento mantélico e fracionamento isotópico [PDF]

open access: yesGeologia USP. Série Científica, 2004
A Seqüência Acamadada Ribeirão dos Motas (SARM) aflora na porção meridional do Cráton São Francisco, na região centro-sul do Estado de Minas Gerais, Brasil.
Maurício Antônio Carneiro   +4 more
doaj   +2 more sources

Staphylococcus aureus resistente a meticilina causante de infecciones comunitarias y de infecciones asociadas a la atención en salud en pacientes pediátricos del Hospital Universitario de Santander

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2014
Introducción. Staphylococcus aureus resistente a la meticilina (SARM) es un agente frecuente de infección en la población pediátrica. Aunque inicialmente las cepas de SARM estaban restringidas a los hospitales, se han reportado a nivel mundial brotes de ...
Mayra Alejandra Machuca   +2 more
doaj   +1 more source

Development of selective androgen receptor modulators (SARMs) [PDF]

open access: yesMolecular and Cellular Endocrinology, 2018
The Androgen Receptor (AR), a member of the steroid hormone receptor family, plays important roles in the physiology and pathology of diverse tissues. AR ligands, which include circulating testosterone and locally synthesized dihydrotestosterone, bind to and activate the AR to elicit their effects.
Ramesh Narayanan   +2 more
openaire   +2 more sources

Colonización por Staphylococcus aureus resistente a la meticilina en una unidad de cuidados intensivos de adultos de un hospital colombiano: caracterización fenotípica y molecular con detección de un clon de circulación en la comunidad

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2010
Introducción. Staphylococcus aureus resistente a la meticilina (SARM) causa infecciones adquiridas en la comunidad y en el ámbito hospitalario. El ser portador de SARM se ha descrito como factor de riesgo para desarrollar infección clínica.
Narda María Olarte   +6 more
doaj   +1 more source

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