Results 1 to 10 of about 11,540 (164)

Transgene sequence codon optimization and composition determines replication competence of self-amplifying RNA. [PDF]

Mol Ther
Bathula NV, Soriano SKV, Huang C, Jan E, Sagan SM, Blakney AK.   +5 more
europepmc   +1 more source

Efficient production of a self-amplifying RNA vaccine sequence with the single subunit RNA polymerase from <i>Klebsiella</i> phage 32 utilizing the native AU initiating dinucleotide. [PDF]

RNA
Price MA, Trubitsyna M, Paget JE, Baker BW, Turner F, Rosser SJ.   +5 more
europepmc   +1 more source

A low-dose self-amplifying mRNA vaccine encoding HPV16 E6/E7 induces potent T-cell immunity and antitumor protection in mice. [PDF]

Cancer Immunol Immunother
Xing R, Wang S, Wang Y, Chen G, Zhou R, Wang X, Ma L, Yang Y, Li S, Zhao M, Zhang Y, Fu Y, Cui F, Meng G, Zheng B, Xiong C, Wang Y.   +16 more
europepmc   +1 more source

Construction of a self-amplifying mRNA-LNP complex for phenylalanine hydroxylase and its efficacy evaluation in gene therapy for phenylketonuria. [PDF]

iScience
Wen Z, Long Y, Shi W, Song W, Xu R, Zhan X, Wang X, Su R, Wang Y, Fei J.   +9 more
europepmc   +1 more source

Sindbis virus self-amplifying replicon is compatible with modified nucleotides mediating expression and vaccine responses <i>in vivo</i>. [PDF]

Mol Ther Adv
Azizi H, Agbayani G, Renner TM, Simard B, Iqbal U, Dudani R, Jia Y, McCluskie MJ, Akache B.   +8 more
europepmc   +1 more source

Engineering drug-responsive replication machinery for precise control of self-amplifying RNA. [PDF]

Nat Biomed Eng
Yousefpour P, Gregory JR, Si K, Lonzaric J, Li Y, Wang J, Qureshi K, Ledbetter A, Melo MB, Hostetler A, Lemnios AA, Dye J, Rodriguez L, Remba TK, Yeung R, Güereca M, Zhang Y, Wu S, Dong Y, Weiss R, Irvine DJ.   +20 more
europepmc   +1 more source

A self-amplifying RNA vector based on rubella virus for mRNA therapeutics and vaccine applications. [PDF]

Mol Ther Nucleic Acids
Jing M, Law MCY, Phung CD, He Y, Tan YB, Le MTN, Luo D.   +6 more
europepmc   +1 more source

β-cell-targeted RNA activation of vascular endothelial growth factor-A improves islet transplantation. [PDF]

Signal Transduct Target Ther
Van Simaeys D, Berggren PO.
europepmc   +1 more source

A Self-Amplifying RNA Lipid Nanoparticle (saRNA-LNP) Vaccine Provides Effective Protection Against Porcine Epidemic Diarrhea. [PDF]

Transbound Emerg Dis
Shu J, Zhang H, Wang F, Zhang H, Liu X, Liu K, Zha Y, Chai W, Yao J, Lin Y, Wu C, Zhao X.   +11 more
europepmc   +1 more source

Working So Hard: Double-Stranded RNAs That Can Perform Both Gene Activation and Gene Silencing. [PDF]

Chembiochem
Chiu VW, Hammill ML, Elabed M, Varley S, Lomonosova Y, Hoare J, Voutila J, Hansen H, Koch T, Desaulniers JP.   +9 more
europepmc   +1 more source