Results 21 to 30 of about 54,039 (182)
RNA Activation—A Novel Approach to Therapeutically Upregulate Gene Transcription
Molecules, 2021 RNA activation (RNAa) is a mechanism whereby RNA oligos complementary to genomic sequences around the promoter region of genes increase the transcription output of their target gene.
Choon Ping Tan +4 more
doaj +1 more source
C/EBPα Short-Activating RNA Suppresses Metastasis of Hepatocellular Carcinoma through Inhibiting EGFR/β-Catenin Signaling Mediated EMT. [PDF]
PLoS ONE, 2016 Hepatocellular carcinoma is associated with high mortality, and tumor metastasis is an important reason for poor prognosis. However, metastasis has not been effectively prevented in clinical therapy and the mechanisms underlying metastasis have not been ...
Hongbo Huan +7 more
doaj +1 more source
Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]
, 2012 It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J +7 more
core +4 more sources
Revista médica (Colegio de Médicos y Cirujanos de Guatemala), 2020 La sarna noruega es una forma aguda de la sarna que se observa en pacientes inmunosupresos. A continuación se presenta el caso de un paciente de 73 años con antecedente de insuficiencia renal con diagnóstico de sarna noruega.
Rosmin Del Pilar Marroquín Remón +3 more
openaire +2 more sources
Scientific Reports, 2023 Self-amplifying messenger ribonucleic acid (saRNA) provides extended expression of genes of interest by encoding an alphavirus-derived RNA replicase and thus is 2–3 times larger than conventional messenger RNA.
Irafasha C. Casmil +2 more
doaj +1 more source
A self-amplifying RNA vaccine against COVID-19 with long-term room-temperature stability
npj Vaccines, 2022 mRNA vaccines were the first to be authorized for use against SARS-CoV-2 and have since demonstrated high efficacy against serious illness and death. However, limitations in these vaccines have been recognized due to their requirement for cold storage ...
Emily A. Voigt +14 more
doaj +1 more source
Revista de la Facultad de Ciencias Médicas de Córdoba, 2018 Crusted scabies is a clinical variant of classical scabies, which is an infestation of the skin by the mite Sarcoptes scabie, Infrequent with high mite burden, usually in people with reduced cellular immunity or elderly long-term care residents. Cutaneous findings are erythematous patches, with prominent scales, usually located in hands, feet, scalp ...
Hora Matias Castro, Maite Lisa Eliceche
openaire +3 more sources
New evolutionary sequences for extremely low mass white dwarfs: Homogeneous mass and age determinations, and asteroseismic prospects [PDF]
, 2013 We provide a fine and homogeneous grid of evolutionary sequences for He-core white dwarfs with masses 0.15-0.45 Msun, including the mass range for ELM white dwarfs (
Althaus, Leandro G. +2 more
core +3 more sources
Intestinal neuromuscular function after preservation and transplantation [PDF]
, 1996 While it is well known that prolonged preservation of the intestinal graft causes severe mucosal damage after transplantation, little is known about the effect on neuromuscular function.
Hamada, N +7 more
core +1 more source